Sensory Rehabilitation in Chemotherapy Induced Peripheral Neuropathy (CIPN)

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05382520

Enrollment

Registered

2022-05-19

Start date

2022-08-01

Completion date

2025-12-01

Last updated

2026-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CIPN

Keywords

Neuropathic pain, Chemo Induced Peripheral Neuropathy (CIPN), Sensory rehabilitation, Explicit Sensory Retraining

Brief summary

Physiotherapist research about Sensory rehabilitation in chemotherapy induced peripheral neuropathy (CIPN) with the aid of questioners and physiotherapy practice

Interventions

DIAGNOSTIC_TESTQuestionares and practice

Questionares and practice

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

OTHER

Masking

NONE

Intervention model description

Prospective Pilot and Feasibility study

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Healthy volunteers

Inclusion criteria

* Patients aged 18 and over who suffer from chemotherapy-induced neuropathy (CIPN), according to the patient's report, more than 3 months since the end of the chemotherapy treatment.

Exclusion criteria

1. Sensory damage / neuropathy that existed even before the start of chemotherapy 2. Incidents of recurrent falls even before the start of chemotherapy (over 2 falls for 6 months) 3. Central nervous system involvement 4. Major pre-morbid orthopedic lower limb impairment 5. Hebrew language not sufficient for assessment and treatment

Design outcomes

Primary

Measure	Time frame	Description
TNAS	2 years	TNAS -Treatment-Induced Neuropathy Assessment Scale. 0-90. higher score = worse status
VAS	2 years	0-100 mm visual scale: self-reporting pain assessment from no pain to worst pain possible. We will ask for current pain and the worst pain during the last week.
FABS	2 years	Fullerton Advanced Balance Scale: high function balance test - consisting of 10 activities in both static and dynamic phases; 10-40, higher scores are better.
TUG	2 years	Timed Up and Go: fall prediction screening test; measures time taken to raise from a chair walking 3 meters and re-sit.
NSA	2 years	Nottingham Sensory Assessment: sensory detection and discrimination test
Semmes-Weinstein monofilament testing	2 years	tactile detection threshold
LEPT	2 years	Lower Extremity Position Test: proprioception detection and quantification
Allodynia	2 years	tested by non-painful mechanical stimulation: gentle brushing and monofilament

Countries

Israel

Contacts

PRINCIPAL_INVESTIGATORRotem Merose, Dr.

Assaf Harofee MC

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 5, 2026