Prostate Cancer
Conditions
Brief summary
Worldwide, prostate cancer is the most commonly diagnosed male cancer and the fourth leading cause of cancer death in men. Risk stratification is according to cancer stage, Gleason score, and PSA level . Definitive treatment of localized disease ( low and favorable intermediate risk) includes watchful waiting , active surveillance , radiation therapy , radical prostatectomy and cryotherapy .Primary treatment of unfavorable intermediate risk , high risk localized disease and locally advanced prostate cancer , includes both radical prostatectomy (RP) and EBRT + long-term androgen deprivation therapy (ADT) .Treatment options of metastatic prostate cancer include pain medications, bisphosphonates, hormonal treatment, chemotherapy, radiotherapy, immunotherapy, focused radiation, and other targeted therapies .
Interventions
outcome of hormonal treatment as androgen deprivation therapy on prostate cancer patient on survival and relapse
outcome of radiotherapy as external beam radiotherapy on prostate cancer patient on survival and relapse
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients at age of 18 years old and above. * All stages and grades of prostate cancer. * Epithelial types of prostate cancer.
Exclusion criteria
* Age below 18 years old. * Presence of other malignancies.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| overall survival | 6 months | Overall survival defined as the time from the date of diagnosis to the last date seen . |
| progression free survival | 6 months | Progression-free survival defined as the length of time during and after the treatment of cancer that a patient lives with the disease but it does not get worse. |
| disease free survival | 6 months | Disease free survival defined as the time from the end of treatment to the date of first relapse . |
Countries
Egypt