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Milk Versus a Pea-based Beverage for Bone and Muscle Health in Young Athletes

Milk Versus a Pea-based Beverage for Increasing Muscle Mass and Bone Mineral Density During Resistance Training in Adolescent Boys and Girls

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05382026
Enrollment
112
Registered
2022-05-19
Start date
2022-05-24
Completion date
2024-01-31
Last updated
2024-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Atrophy

Brief summary

Canada's Food Guide places an increased emphasis on plant-based proteins; however, Canadians who consume a plant-based diet may be compromised because of intake of lower-quality protein. Consumption of high-quality protein is important during growth and development, especially in highly active individuals. The study will compare milk (i.e. high quality protein) to a pea-based beverage (i.e. lower quality plant-based protein) in adolescent boys and girls who are engaged in resistance-training programs as part of their athletic training. One-hundred and fourteen adolescent boys and girls (12-17y of age) will be divided into groups that consume milk, a pea-beverage, or a carbohydrate (sugar) beverage after resistance training sessions performed three times per week for six months. It is predicted that the group consuming milk will have greater increases in muscle mass, strength, and bone density, and greater reductions in fat mass compared to the groups consuming a pea-based or carbohydrate beverages.

Detailed description

Milk protein is important especially for very active people and in the context of plant-based diets, which are lower in protein quality. The purpose of the study is to compare the effectiveness of milk supplementation to pea-beverage supplementation during resistance training programs for increasing lean tissue mass in adolescent boys and girls. Secondary and tertiary outcomes include fat mass, bone mineral density, and muscular strength. It is hypothesized that milk supplementation during resistance training will be more effective than plant-based proteins (i.e. pea-beverage) for increasing muscle mass, reducing fat mass, and improving bone mineral outcomes in adolescent boys and girls. One-hundred and fourteen boys and girls (aged 12-17y) who are currently enrolled in resistance training programs (3 times per week for 6 months) as part of their competitive athletic programs will be stratified by sex and maturity status before being randomized to three groups: 1) 1% chocolate milk supplementation; 2) pea-based beverage; 3) carbohydrate beverage (placebo control). Beverages will be consumed during recovery from each resistance training session (i.e. 250 ml immediately after training and 250 ml one hour later to optimize post-exercise protein synthesis) over the six-month intervention. It is anticipated that milk supplementation will be more effective than plant-based protein supplementation.

Interventions

DIETARY_SUPPLEMENTNutritional supplementation during a 6 month resistance training program

1% chocolate milk

Sponsors

University of Saskatchewan
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
12 Years to 17 Years
Healthy volunteers
Yes

Inclusion criteria

* Currently participating in a resistance-training program 3 times per week * Female participants must have reached menarche

Exclusion criteria

* Have taken any nutritional supplement (e.g., protein, creatine, amino acids) within the past month * Currently taking anabolic steroids or oral corticosteroids * Allergies to dairy, almonds, cashews, or peas

Design outcomes

Primary

MeasureTime frameDescription
Change in lean tissue mass (kg)6 monthsLean tissue mass measured by dual energy X-ray absorptiometry

Secondary

MeasureTime frameDescription
Change in section modulus at the hip (cm to the power of 3)6 monthsSection modulus measured by dual energy X-ray absorptiometry
Change in cross-sectional area at the hip (cm-squared)6 monthsCross-sectional area measured by dual energy X-ray absorptiometry
Change in cortical thickness at the hip (cm)6 monthsCortical thickness measured by dual energy X-ray absorptiometry
Change in fat mass (kg)6 monthsFat mass measured by dual energy X-ray absorptiometry
Change in buckling ratio at the hip (no units)6 monthsBuckling ratio measured by dual energy X-ray absorptiometry
Change in hip bone mineral density (g/cm-squared)6 monthsHip bone mineral density measured by dual energy X-ray absorptiometry
Change in bench press strength (kg)6 monthsBench press strength predicted from resistance lifted for 6-10 repetitions
Change in squat strength (kg)6 monthsSquat strength predicted from resistance lifted for 6-10 repetitions
Change in cross-sectional moment of inertia at the hip (cm to the power of 4)6 monthsCross-sectional moment of inertia measured by dual energy X-ray absorptiometry
Change in lumbar spine bone mineral density (g/cm-squared)6 monthsLumbar spine bone mineral density measured by dual energy X-ray absorptiometry

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026