Haematological Malignancy
Conditions
Brief summary
It is a study about adaptated physical activity for patients receiving a stem cell transplantation. They will benefit of 6 adaptated individuals lessons at home between 1 month and 3 months after stem cell transplantation. The study's goal is to observe if adaptated activity has an positive impact on weight loss and on life quality.
Interventions
OTHER6 sessions of adapted physical activity after stem cell transplant
physical assessement before and after stem cell transplant: * weight loss * brachial muscle circumference * grip strength evaluation * short physical battery test psychometric assessment before and after stem cell transplant: * quality of life questionary * physical activities questionary
Sponsors
Centre Hospitalier Universitaire de Nice
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
: * Patient aged 18 or more * Patient with social security * Patient who accept the study and sign the consent form * Patient programmed for an allogenic stem cell transplantation Non inclusion criteria : * Patients with a guardianship * Patients with a significant additional physic or mental disease
Exclusion criteria
* Patients who did not receive an allogeniac stem cell transplantation * Patients still hospitalized between day 30 and day 100 after stem cell transplantation * Patients who finally refuses the study * Patients who develop a physical or mental incapacity to practice physical activity
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| weight loss | before stem cell transplantation, 1 month , 3 months, 1 year after stem cell transplantation | Body weight n in kilograms |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| body mass index | before stem cell transplantation, 1 month , 3 months, 1 year after stem cell transplantation | Measure of weight and height to evaluate the nutriotional status of a patient |
| brachial muscle circumference | before stem cell transplantation , 1 month , 3 months, 1 year after stem cell transplantation | evaluation in centimeters of the brachial circumference to evaluate the evolution of the muscle circumference after stem cell transplantation and adaptated physical activity compared to the evaluation before stem cell transplantation. Using a measuring tape |
| grip strength evaluation | before stem cell transplantation , 1 month , 3 months, 1 year after stem cell transplantation | it is a measure of muscular strength |
| patient's ability to attend the classes | 3 months after stem cell transplantation | number of adaptated physical activity lessons attended by each patient after stem cell transplantation, calculation of feasibility |
| Quality of Life Questionary C30 (QLQ-C30) | before stem cell transplantation , 1 month , 3 months, 1 year after stem cell transplantation | it is a score to evaluate the quality of life of patients facing illness The subscales scores are transformed to a 0 to 100 scale, with higher score on functionnal scales indicating better function and higher scores on sumptom scales indicating worse symptoms |
| in house developped physical activities questionary | before stem cell transplantation , 1 month , 3 months, 1 year after stem cell transplantation | it is a questionnary created especially for this study to evaluate on each step the capacity of each patient to maintain physical activities (social activities, autonomy at home for cooking and hygiene care, autonomy for transport to go to hospital appointments) |
| short physical battery test | before stem cell transplantation , 1 month , 3 months, 1 year after stem cell transplantation | it is a series of 3 physical tests to evaluate mobility the first test is a balance test (4 points), the second test is an evaluation of a walking speed (4 points) and the third test is a Chair rise test (4 points) The global test is on 12 points (12 is the better score) |
Countries
France
Contacts
Primary ContactSOLDATI Alizée
Backup ContactLOSCHI Mickael, MD
Outcome results
None listed