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Davos Alzheimer's Collaborative Study: Sequential Administration of Digital Testing To Screen For Cognitive Impairment Followed By Blood Based Biomarkers To Assist With Timely Detection And Accurate Diagnosis Of Alzheimer's Disease

Davos Alzheimer's Collaborative Study: Sequential Administration of Digital Testing To Screen For Cognitive Impairment Followed By Blood Based Biomarkers To Assist With Timely Detection And Accurate Diagnosis Of Alzheimer's Disease

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05379348
Acronym
DAC
Enrollment
1423
Registered
2022-05-18
Start date
2022-03-14
Completion date
2025-08-05
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer Disease

Brief summary

The purpose of this study is to investigate how we can detect Alzheimer's disease early by using an online memory test and a simple blood test. These new methods for early diagnosis could allow people to begin treatment sooner, with the potential to improve the lives of millions of people.

Interventions

OTHERCognitive Assessment

Montreal Cognitive Assessment - MoCA, which is a cognitive screening tool that assesses: memory, concentration, language, and orientation to time and place. this written cognitive test should take no more than 20 minutes.

Sponsors

AdventHealth Translational Research Institute
Lead SponsorOTHER
Davos Alzheimer's Collaborative
CollaboratorUNKNOWN

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Subjects must meet the following criteria for entry into the study: 1. Male or female \> 65 years of age at the time of consent; 2. Understand and voluntarily sign an informed consent form; Inclusion criteria is assessed at both e-consent (assessed by participant's self-reporting of age and understanding) and in-person consent at TRI (assessed by clinical research coordinators in TRI).

Exclusion criteria

Subjects who meet any of the following criteria will not be eligible for entry into the study: 1. Subjects who are unable to hear and see well enough to complete the assessments; 2. Prior diagnosis of dementia or Alzheimer's disease documented in their medical record and/or as diagnosed by a physician;

Design outcomes

Primary

MeasureTime frame
Quantify the proportion of individuals at least 65 years old with cognitive impairmentLess than 6 months

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORSteven Smith, MD

Study PI

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 31, 2026