Multiple Sclerosis Intimacy and Sexuality Questionnaire

The Multiple Sclerosis Intimacy and Sexuality Questionnaire-15 (MSISQ-15): Validation of the Turkish Version in Patients With Multiple Sclerosis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05374031

Enrollment

130

Registered

2022-05-13

Start date

2021-08-12

Completion date

2022-03-10

Last updated

2022-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis, Questionnaires, Sexual Dysfunction

Keywords

Multiple sclerosis, questionnaires, sexual dysfunction, self-report

Brief summary

Aims: This study aimed to psychometrically evaluate the Turkish version of the Multiple Sclerosis Intimacy and Sexuality Questionnaire (MSISQ-15) in women with MS. Methods: The study included 130 women with MS. The Turkish linguistic validation process of the original English MSISQ-15 was performed according to standardized guidelines. Reliability analysis was evaluated with test-retest analysis and intra-class correlation (ICC). Internal consistency between the items was analyzed using the Cronbach's alpha coefficient. Item analysis results were used to assess the contribution of the items to the scale. In evaluating the validity of the scale, the relationship between the MSISQ and the Female Sexual Function Index (FSFI), the Multiple Sclerosis Quality of Life Questionnaire-54 (MSQOL-54), and the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PSIQ-12) was investigated. Psychometric properties were analyzed using internal consistency, test-rest reliability, construct validity, and floor-ceiling effect.

Interventions

OTHERdescriptive study

descriptive study

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

19 Years to 64 Years

Healthy volunteers

Yes

Inclusion criteria

* Women over the age of 18 who were literate, * who did not have any mental problems preventing cooperation and understanding, * who were diagnosed with MS

Exclusion criteria

* Having pelvic organ prolapse stage 2 or more; * having a history of relapse in the past 30 days; * experiencing loss of balance or gait disturbance caused by a condition other than MS; * being pregnant; having a history of gynecological, urological and/or neurological surgery; * having a history of cesarean or vaginal birth in the past six months; * being sexually inactive; and, having urinary tract infections

Design outcomes

Primary

Measure	Time frame	Description
Questionnaire	day 1	Multiple Sclerosis Intimacy and Sexuality Scale is a 15-item self-report measure that assesses the impact of MS symptoms on sexual activity and satisfaction over the past 6 months.Higher scores indicate greater sexual problems.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026