Clinical Outcome
Conditions
Keywords
nutritional index, brain tumor surgery, mortality
Brief summary
There are several predictors of clinical outcome in patients undergoing brain tumor surgery. Among those, nutritional parameters and calculated nutritional index are known to have ability to predict mortality and clinical outcomes in some patients with brain tumor. However, there are lack of consistent results on predictability of nutritional index and clinical outcome in patients undergoing brain tumor surgery.
Detailed description
In this retrospective study, we evaluated the relationship between prognostic nutritional index, which was calculated from laboratory parameters, and clinical outcome including mortality in patients undergoing brain tumor surgery.
Interventions
DIAGNOSTIC_TESTprognostic nutritional index calculated from laboratory parameters
Calculated nutritional index using laboratory results of serum albumin, lymphocyte count, and cholesterol
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* adult patients undergoing brain tumor surgery at Seoul National University Hospital, South Korea
Exclusion criteria
* Lack of results of laboratory parameters, such as serum albumin, lymphocyte count, cholesterol * Lack of data on clinical outcome, including mortality, acute kidney injury, renal replacement therapy, length of hospital stay, and other major adverse outcome
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| predictability of prognostic nutritional index for mortality after brain tumor surgery | From date of surgery until the date of death from any cause, whichever came first, assessed up to 50 years | Odds ratio of prognostic nutritional index for postoperative mortality |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| predictability of prognostic nutritional index for acute kidney injury after brain tumor surgery | From date of surgery until the date of acute kidney injury from any cause, whichever came first, assessed up to 50 years | Odds ratio of prognostic nutritional index for postoperative acute kidney injury |
| predictability of prognostic nutritional index for renal replacement therapy after brain tumor surgery | From date of surgery until the date of renal replacement therapy from any cause, whichever came first, assessed up to 50 years | Odds ratio of prognostic nutritional index for postoperative renal replacement therapy |
| relationship of prognostic nutritional index for length of hospital stay after brain tumor surgery | From date of surgery until the date of hospital discharge | Odds ratio of prognostic nutritional index for length of hospital stay |
Countries
South Korea
Contacts
PRINCIPAL_INVESTIGATORYoun Joung Cho, MD, PhD
Seoul National University Hospital
Outcome results
None listed