Incidence and Risk Factors of Low Anterior Resection Syndrome
Conditions
Brief summary
Low anterior resection syndrome (LARS) frequently occurs in patients undergoing low anterior resection (LAR). However, the incidence, exact mechanism and risk factors of major LARS largely variate in different studies. Considering varieties and differences of patient characteristics between Chinese patients and the western ones, this retrospective study aims to investigate the incidence of LARS in Chinese patients undergoing laparoscopic LAR, and to explore perioperative risk factors that might be associated with major LARS. Consequent patients undergoing laparoscopic LAR and free from disease recurrence from January 2015 to May 2021 were issued with LARS questionnaire. Incidence of LARS and patient data were collected and analyzed.
Interventions
DIAGNOSTIC_TESTLARS questionnaire
Eligible participants were issued with LARS questionnaire (Chinese version) by E-mail, message, phone or face to face interview.
Sponsors
Third Affiliated Hospital, Sun Yat-Sen University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
Patients diagnosed as rectal cancer and underwent radical laparoscopic LAR and straight colorectal/coloanal anastomosis (with or without a protective stoma) by a same surgical team
Exclusion criteria
either local or distal recurrence, severe complications such as postoperative anastomotic leakage, failure of protective stoma closure, data missed and no responding to LARS questionnaire
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| incidence of LARS | at least 1 months postoperatively | incidence of Low Anterior Resection Syndrome |
| incidence of major LARS | at least 1 months postoperatively | incidence of major Low Anterior Resection Syndrome |
Countries
China
Outcome results
None listed