IVF
Conditions
Brief summary
Infertility is a disease that seriously affects the physical and mental health of women of childbearing age. The incidence of infertility has been increasing in recent years. Studies have shown that the occurrence of infertility may be related to environmental endocrine disrupting substances. This project was designed to establish a cohort study on environmental endocrine disrupting substances and in vitro fertilization (IVF) treatment, collect blood, urine, semen, follicular fluid, granulosa cells, chorionic decidua biological specimens, and then follow up on the pregnancy outcomes. The concentration of disrupting substances was detected and then found the associations between environmental endocrine disrupting substances and female reproductive health.
Interventions
there is no intervention in the study
Sponsors
Peking University People's Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
Clinical diagnosis of infertile patients undergoing IVF treatment
Exclusion criteria
Donor egg transplants excluded
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of eggs retrieved | immediately after the eggs retrieved | the number of eggs retrieved in the process of in vitro fertilization (IVF) |
| the number of available embryos | 1 week after the eggs retrieved | the number of available embryos in the process of IVF |
| the clinical pregnancy rate | 4 weeks after the embryos transfer | the clinical pregnancy rate in the process of IVF |
| the miscarriage rate | 7 months after embryos transfer | the miscarriage rate in the process of IVF |
| the live birth rate | 40 weeks after embryos transfer | the live birth rate in the process of IVF |
Countries
China
Contacts
Primary ContactHuan Shen, Doctor
Outcome results
None listed