Obesity
Conditions
Brief summary
The EXDECHO study is the first randomized study evaluating the effect of four body positions on diaphragmatic excursion in obese patients by ultrasound. The investigators suppose that the course of the right diaphragmatic hemicupola would be increased by an increasingly horizontal position (gradual increase in the diaphragmatic excursion from standing to lying down). If this hypothesis is confirmed, kinesitherapists will have more informed positioning choices to improve the effectiveness of respiratory rehabilitation.
Interventions
OTHERMeasurement of the diaphragmatic excursion according to the position of the body by ultrasound
Measurement of the diaphragmatic excursion according to the position of the body by ultrasound
Sponsors
Central Hospital, Nancy, France
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* to have a BMI greater than or equal to 30; * to have not had intense physical activity during the hour preceding the measurements; * to be enrolled in a social security plan; * to give a written consent; * to have underwent a pre-inclusion medicalexamination.
Exclusion criteria
* to have a respiratory pathology unrelated to obesity (sleep apnea syndrome, obesity-hypoventilation syndrome, restrictive ventilatory syndrome with no other known cause); * to have a cardiac pathology not stabilized by drug treatment and/or resulting in heart failure and/or requiring the fitting of a pacemaker or defibrillator; * to have a chronic inflammatory disease (rheumatoid arthritis, Crohn's disease, cirrhosis, etc.); * to have a chest deformity (kyphoscoliosis, funnel chest, etc.); * to be anactive smoking or former smoker (stopped for less than 3 months and total consumption \> 10 pack-years); * to have an history of major surgery, surgery under general anesthesia for less than 3 months, or minimally invasive surgery for less than 1 year of the thoraco-abdomino-pelvic compartments; * to have a known sensitivity to monopropylene glycol (substance present in the sterile ultrasound gel); * temperature of the room in which the ultrasound measurements are carried out below 20°C or above 25°C; * subject under a measure of legal protection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragmatic excursion in centimeters in the 4 positions measured by ultrasound | Day 0 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between measurement of diaphragmatic excursion in centimeters by ultrasound and weight in kilograms. | Day 0 | — |
| Correlation between measurement of diaphragmatic excursion in centimeters by ultrasound and waist circumference in centimeters. | Day 0 | — |
| Correlation between measurement of diaphragmatic excursion in centimeters by ultrasound and BMI in kg/m². Weight in kilograms and height in meters will be combined to report BMI in kg/m². | Day 0 | — |
| Correlation between measurement of diaphragmatic excursion in centimeters by ultrasound and sex of the participant (male/female). | Day 0 | — |
| Comfort of the ultrasound examination felt by the patient via a questionnaire | Day 0 | Positions, duration of the examination, pressure exerted by the probe: score from 0 (unpleasant) to 4 (acceptable) |
Countries
France
Contacts
Primary ContactMarine Mervelet
Outcome results
None listed