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Cardiac Assessment in Obese and Overweight Children

Cardiac Assessment of Obese and Overweight Children Attending Asyut University Children Hospital

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05371821
Enrollment
50
Registered
2022-05-12
Start date
2022-05-20
Completion date
2023-05-31
Last updated
2022-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Childhood

Brief summary

Is to assess cardiac functions of overweight and obese children attending assiut University children hospital in one year duration .

Detailed description

The prevalence of overweight and obesity in children is increasing worldwide at an alarming rate in both developing and developed countries .the relation between obesity and cardiac structure and function in children is less well documented and conflicting results have been reported .In addition, obesity is associated with a heterogeneity of metabolic abnormalities , (e.g., dyslipidemia , insulin resistance hyperglycaemia and hypertension , that may provide a plausible biologic link between obesity and the increased risk of cardiovascular morbidity and mortality .The clustering of these risk factors for cardiovascular disease is referred to as the metabolic syndrome. Although the concept and definition of the metabolic syndrome are controversial at the moment, there is no doubt that a cluster of cardiovascular risk factors is present in obese children and adolescents and that their presence increases with worsening obesity .children are likely to be the ideal candidates for providing insight into the myocardial changes related to obesity because they are suggested to be free of other cardiovascular risk factors indifferent echocardiographic studies .

Interventions

DEVICEEchocardiography

Echocardiographic parameters in obese and overweight

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
2 Years to 18 Years
Healthy volunteers
Yes

Inclusion criteria

1. \- Age: children at 2-18 years . 2. \- Overweight children whose body mass index at or above the 85th percentile and below the 95th percentile for the same age and sex 3. \- Obese children whose body mass index at or above the 95th percentile for the same age and sex.

Exclusion criteria

1- Obese children below two years 2 - Cases with syndromic obesity, diabetes * thyroid and parathyroid and those with congenital heart diseases

Design outcomes

Primary

MeasureTime frameDescription
Cardiac assessment of obese and overweight childrenBaselineEchocardiography performed by an expert cardiologist using a Philips envisor c machine to assess the following parameters (left ventricle end-diastolic diameter (LVEDD), left ventricle end-systolic diameter (LVESD), interventricular septal systolic diameter (IVSSD), interventricular septal diastolic diameter (IVSDD) left ventricle fraction shortening (FS), left ventricle ejection fraction (EF), left atrium to aorta ratio (LA:AO), mitral annular plane area systolic excursion (MAPSE), fraction area shortening of the right ventricle (FAC), tricuspid annular plane systolic excursion (TAPSE)
Assessment of body mass indexbaselineBMI described in kg / m²

Contacts

Primary ContactOsman G Hassan, MD
osmanelsafawy@gmail.com+201019058968
Backup ContactOsama M Al Asheer, Professor
osamaelasheer@med.edu.eg+201001348864

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026