Pain, Chronic
Conditions
Brief summary
hyalase and dexmedtemodine are well known adjuvants given epidurally to alleviate chronic back pain. Use in failed back surgery is an up to date field to hasten analgesia and py off recurrence .
Interventions
DRUGHylase versus dexmedtemodine
fluroscopic guided lumber epidural injection
Sponsors
Minia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
30 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Age group. 25-75ys old * Both sex. * persistent (at least 6 month) pain and or disability following laminectomy with or without sensory-motor neurological deficits or any form of urinary or bowel incontinence * Patients suffering from persistent (\> 6 months) back pain following laminectomy for spinal canal stenosis and/or discectomy for herniated nucleus pulposus documented by magnetic resonance imaging (MRI) were included for screening and enrollment.
Exclusion criteria
* Diabetic patients. * Refusal to participate * MRI with disc sequestration, concurrent sacro-ilitis, facet arthropathy . * Coagulopathic patients * Surgical induced discitis.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pain assesment | 6 months | Visual analogue scale... 0= no pain .... 10= worst pain |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| functional disability | 6 months | Modified oswestry diability questionnaire. 0% to 20%: minimal disability:....21%-40%: moderate disability: 41%-60%: severe disability...61%-80%: crippled |
| acute complications | 6 hours | number of patients with epidural hematoma |
Countries
Egypt
Outcome results
None listed