Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy
Conditions
Keywords
methylene blue, spraying, intraoperative, thyroidectomy
Brief summary
Impact of Intraoperative Spraying methylene blue In thyroidectomy
Detailed description
General anaesthesia ,supine position with hyperextension to the neck Low collar incision to the neck , incision to the skin and platysma muscle and fascia ,upper and lower flaps are developed ,separation of strap muscles and identification of the thyroid gland after freeing of investing fascia Ligation of the middle thyroid vein and ligation and separation of the superior pedicle away from the external laryngeal nerve At this point of operation and before ligation of inferior pedicle, methylene blue 0.05% spraying is applied to the field the amount varies according to size of the thyroid lobe and variation in population and neck size Thyroid gland stained by bluish color , recurrent laryngeal nerve not stained or minimally stained so we can avoid injury to it parathyroid glands get red of the stain after about 3 minutes so we can avoid injury to it thyroid gland lose its stain in about 15 minutes so we can remove any residual and decrease residual tissue or recurrence
Interventions
PROCEDUREImpact of Intraoperative Spraying Methylene Blue In Thyroidectomy
General anaesthesia ,supine position with hyperextension to the neck Low collar incision to the neck , incision to the skin and platysma muscle and fascia ,upper and lower flaps are developed ,separation of strap muscles and identification of the thyroid gland after freeing of investing fascia Ligation of the middle thyroid vein and ligation and separation of the superior pedicle away from the external laryngeal nerve At this point of operation and before ligation of inferior pedicle methylene blue 0.05% spraying is applied to the field the amount varies according to size of the thyroid lobe and variation in population and neck size Thyroid gland stained by bluish color , recurrent laryngeal nerve not stained or minimally stained so we can avoid injury to it parathyroid glands get red of the stain after about 3 minutes so we can avoid injury to it thyroid gland lose its stain in about 15 minutes so we can remove any residual and decrease residual tissue or recurrence
Sponsors
Qena Oncology Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy
Eligibility
Sex/Gender
ALL
Age
15 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Both sexes * Age more than 15 years * All pathologies need surgery eg. (mutinodular goiter, malignancy , thyroid nodule,…..etc * Total thyroidectomy
Exclusion criteria
* Pregnant females * Previous neck surgery or recurrent thyroid surgery * Subtotal or partial thyroidectomy * Age less than 15 years * Preoperative affection to vocal cord * Preoperative hypocalcaemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Operative time | 1 day |
| Presence of residual or recurrence | 3 months |
| Recurrent laryngeal nerve injury | 2 weeks |
| Parathyroid gland Injuries | 3 months |
| Intraoperative injury to trachea | 2 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Stridor | 3 months | temporary or permanent (by clinical evaluation and vocal cord examination) |
| Hypoparathyroidism | 3 months | temporary or permanent (level of para thormone hormone ) |
| Hypocalcaemia | 3 months | temporary or permanent ( level of total and free serum calcium ) |
| Hoarseness of voice | 3 months | temporary or permanent (by clinical evaluation and vocal cord examination) |
Contacts
Primary ContactMohamed Ahmed Orabi, Specialist Surgical Oncology
Backup ContactAmr M Makky, Specialist Surgical Oncology
Outcome results
None listed