The Contributions of the Multidisciplinary Management of Prosthesis Knee Infections in a Reference Center: A Retrospective Study About 52 Cases.Skin Coverage in a Reference Center: A Retrospective Study About 52 Cases

The Contributions of the Multidisciplinary Management of TKA Infections in a Reference Center: A Retrospective Study About 52 Cases.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05367726

Enrollment

Registered

2022-05-10

Start date

2022-05-01

Completion date

2022-09-01

Last updated

2022-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Flap Necrosis, Knee Joint Prosthesis Infection, Skin Graft Complications

Keywords

knee joint prosthesis, Flap, Skin Graft

Brief summary

Acute and chronic infection of knee joint prosthesis can have several outcomes, the most feared of which is trans-femoral amputation. In order to save the limb while maintaining function, the management of these infections involves several specialists. Orthopedic surgeons are on the front line for carrying out bacteriological samples as well as for changing the material when necessary. The infectiologists coordinate this care by supervising each of the interventions by an antibiotic therapy adapted to the germs and by ensuring the occurrence of adverse events related to the treatment. Plastic surgeons intervene when the skin cover of the knee is deemed to be precarious or when there is an identified loss of substance that could affect the prognosis of the prosthesis. The main objective of our study is to evaluate the success rate of skin coverage and functional recovery for patients cured of their infection. The secondary objective is the identification of risk factors for skin coverage in this population.

Interventions

OTHERpatients having had skin coverage of the knee

the cutaneous cover is not always optimal to protect the prosthesis, an act of reconstructive plastic surgery is then necessary

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Patients with a prosthesis knee infection whose management requires skin covering plastic surgery * Surgical procedures performed at the Croix Rousse Hospital

Exclusion criteria

* none

Design outcomes

Primary

Measure	Time frame	Description
rate of patients with prosthesis knee infection requiring skin coverage	2011-2021	proportion of patients with prosthesis knee infection requiring skin coverage amaong all prosthesis knee infection

Secondary

Measure	Time frame	Description
description of the population at risk of coverage after prosthesis knee infection	2011-2021	rate of failure

Countries

France

Contacts

Primary ContactTristan Ferry, Md,PhD

tristan.ferry@chu-lyon.fr04 26 73 29 38

Backup ContactEugenie Mabrut, CRA

eugenie.mabrut@chu-lyon.fr04 26 73 29 38

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026