Hospitalization, Older Adults
Conditions
Keywords
Exercise, Hospitalization, Older Adults, Physical Functional Performance, Randomized Controlled Trial
Brief summary
This study aims to examine 1) if multicomponent exercise interventions (including both mobility and strengthening exercises) have effects on physical function compared to usual care in older adults, and 2) if a comprehensive multicomponent exercise program is more effective than a simple multicomponent exercise program including only walking and rising from a chair.
Detailed description
This is a three-armed randomized controlled trial, with two intervention groups (comprehensive and simple exercise program) and a control group receiving usual care. Participants aged ≥75 years will be included consecutively from geriatric medical wards of hospitals in Stockholm, Sweden. Assessments will be conducted at hospital admission, discharge and three months thereafter concerning physical function (primary outcome), activities of daily living, health-related quality of life, sarcopenia, and falls. Number of re-admissions and mortality will be registered up to 1 year after discharge.
Interventions
OTHERIntervention 1 (simple exercise program)
Up to four sessions per day (total duration 20-30 minutes/day). Performed at the hospital on all weekdays from baseline until hospital discharge (around 1 week). At discharge, the participants will be encouraged to continue with the exercise program at home.
OTHERIntervention 2 (comprehensive exercise program)
Two daily sessions (morning and afternoon) of 20 minutes' duration each. Performed at the hospital on all weekdays from baseline until hospital discharge (around 1 week).
Sponsors
Karolinska Institutet
Swedish Council for Working Life and Social Research
Center for Innovative Medicine
Konung Gustaf V:s och Drottning Victorias Frimurarestiftelse
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
75 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ability to stand up from a sitting position independently or with minimal personal help * ability to communicate and collaborate with the research staff
Exclusion criteria
* people who are not able to follow instructions * people who by the responsible physician are assessed as not eligible to participate due to terminal illness or any major medical condition that contraindicates exercise * those living in nursing home * those previously included in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Physical function | Change from baseline (hospital admission) to completion of the hospital-based exercises (at discharge around 1 week after baseline) | Short Physical Performance Battery (Possible score: 0-12), a higher score represents a better physical function) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Activities of daily living | Change from baseline (hospital admission) to completion of the hospital-based exercises (at discharge around 1 week after baseline) | Barthel Index (Possible score: 0-100, a higher score represents a better functional ability) |
| Health related quality of life | Change from baseline (hospital admission) to completion of the hospital-based exercises (at discharge around 1 week after baseline) | EuroQol-5 Dimension |
| Sarcopenia | Change from baseline (hospital admission) to completion of the hospital-based exercises (at discharge around 1 week after baseline) | Defined by grip strength and calf- and arm circumferences according to the European Working Group's revised criteria on Sarcopenia in Older People |
| Number of falls | Change from baseline (hospital admission) to completion of the hospital-based exercises (at discharge around 1 week after baseline) | According to the logbooks at the hospital |
| Mortality data | Up to 1 year after hospital discharge | Data on vital status will be collected using administrative data |
| Number of readmissions | Up to 1 year after hospital discharge | Data on readmissions will be collected using administrative data |
Countries
Sweden
Outcome results
None listed