Pregnancy Related
Conditions
Keywords
pregnancy, group a streptococci, group b streptococci, carriage, microbiota, Streptococcus pyogenes, Streptococcus agalactiae
Brief summary
This is a prospective clinical study that aims to investigate asymptomatic carriage of beta haemolytic streptococci (especially group A streptococci, GAS and group B streptococci, GBS) during pregnancy. Association of asymptomatic carriage to possible complications of the mother or the newborn as well as the transmission between spouses will be evaluated. Maternal microbiota during labour will also be studied.
Interventions
None listed
Sponsors
University of Turku
Turku University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* pregnant women * partner of the pregnant women * over/equal 18 years of age * willing to participate the study
Exclusion criteria
* multiple pregnancy * age \<18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Carriage of beta haemolytic streptococci | up to 30 weeks | Throat and vaginal carriage of beta haemolytic streptococci (especially GAS and GBS) during pregnancy. Transmission and longitude of the carriage will be evaluated as well. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pregnancy or delivery related infections/complications | up to12 weeks | Patient records of the pregnant women will be surveyed for any complications/infections until 12 week after delivery. Data will be analysed together with the microbiological findings from the women. |
| Infections/complications of newborn | 12 weeks after birth | Patient records are surveyed to search for any infections/complications of the newborn until 12 weeks of age. Data will be analysed together with the findings from their mother. |
Countries
Finland
Outcome results
None listed