Obesity
Conditions
Brief summary
The aim of the study is to compare the effect of a low versus moderate versus high energy turnover on energy intake, appetite and food reward, in adolescents with obesity. 18 adolescents with obesity will then complete three experimental sessions in a randomized order: low, high and moderate Energy turnover.
Detailed description
A total of 18 adolescents with obesity, aged 12-16 years olds will complete three experimental sessions in a randomized order: i) low energy turnover; ii) Moderate energy turnover and ; iii) High energy turnover. Their ad libitum energy intake at dinner will be assessed through an ad libitum buffet-type meal, their food reward assessed right before the dinner meal and their appetite sensation at regular intervals during the day.
Interventions
BEHAVIORALLow energy turnover
Low Energy Turnover. The adolescents with ingest low energy intake at lunch and breakfast and will not perform physical exercise during the day. The will will receive an ad libitum meal at dinner time. Their food reward will be assessed before dinner. Their appetite feelings will be assessed at regular intervals. Moderate Energy Turnover. The adolescents with ingest moderate energy intake at lunch and breakfast and will perform one 45 minutes physical exercise during the day. The will will receive an ad libitum meal at dinner time. Their food reward will be assessed before dinner. Their appetite feelings will be assessed at regular intervals. High Energy Turnover. The adolescents with ingest high energy intake at lunch and breakfast and will perform two 45-minute physical exercises during the day. The will will receive an ad libitum meal at dinner time. Their food reward will be assessed before dinner. Their appetite feelings will be assessed at regular intervals.
Sponsors
University Hospital, Clermont-Ferrand
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
12 Years to 16 Years
Healthy volunteers
No
Inclusion criteria
* BMI percentile \> 97th percentile according to the french curves. * ages 12-16 years old * Signed consent form * being registered in the national social security system * no contraindication to physical activity
Exclusion criteria
Previous surgical interventions that is considered as non-compatible with the study. * Diabetes * weight loss during the last 6 months * cardiovascular disease or risks
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Energy intake measured during an ad libitum buffet meal (in kcal). | it will be assessed at dinner baseline | food intake will be measured ad libitum during a dinner buffet. The adolescents will be offered an ad libitum buffet-type meal composed based on their food intake preferences. Their intake will be weighted using an electronic food scale by a member of the investigation team and then analysed using a nutritional software. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hunger feelings | immediately after breakfast/lunch/dinner on day 1 | hunger area under the curve will be assessed using visual analogue scale through a the day |
| Food reward | it will be assessed at dinner baseline | : The participants will be asked to complete a validated computer-based procedure to measure food reward (Leeds Food Preference Questionnaire; LFPQ). Briefly, the LFPQ provides measures of the wanting and liking for an array of food images, varying in both fat content and taste. |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORYves BOIRIE
University Hospital, Clermont-Ferrand
Outcome results
None listed