Embryo Transfer, Fertility Issues, IVF
Conditions
Brief summary
The primary outcome of the study is to determine if a difference in terms of pregnancy rate exists between direct and afterload embryo transfer (ET) techniques. The secondary end points include the evaluation of the difficult transfer rates.
Detailed description
The study database includes all the single fresh and frozen (G5-G6) blastocyst transfers performed at Humanitas Fertility Centre between 1st January 2016 and 31th December 2021 by using the direct and afterload protocols. Any blastocysts that underwent preimplantation genetic testing will be excluded from the analysis, as well as embryos derived from gamete donation or those imported from other centers. Data are gathered using a specific internal web-based database, which allows to organize, store and readily retrieve information about patients and IVF cycle.
Interventions
None listed
Sponsors
Istituto Clinico Humanitas
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 43 Years
Healthy volunteers
No
Inclusion criteria
* IVF procedure * Fresh and frozen single blastocyst transfer
Exclusion criteria
* Any blastocysts that underwent PGS testing * Embryos derived from gamete donation * Embryos imported from other centers
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical pregnancy rate | 6 years | number of pregnancies diagnosed by ultrasonographic visualization of one or more gestational sacs x 100 divided by the number of embryo transfer cycles |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| difficult transfer rate | 6 years | advancement of the outer sheath, multiple attempts, force, required manipulation, use of a stylet or tenaculum, dilatation, use of a different catheter |
Outcome results
None listed