Hematological Malignancy
Conditions
Keywords
cancer, hematological, malignancy
Brief summary
The purpose of the study is to investigate whether a simple taste-test will increase the intake of energy as part of the individual dietary counseling.
Detailed description
The investigators will investigate the tastes (umami, bitter, salty, sweet and sour) that the patients prefers in order to increase the energy intake and reduce the risk of weight loss and loss of fat-free mass for patients with hematological cancer. The study will be conducted as a single blinded randomized controlled trial. 40 patients will be recruited, and will be divided into two groups; the intervention group and the control group. The patients will not know which group they belong to.
Interventions
DIETARY_SUPPLEMENTTaste-test
Patients will receive a dietary counseling based on a simple taste-test
OTHERStandard care
Patients will receive a dietary counseling based on a standard dietary counseling for the patient group
Sponsors
Zealand University Hospital
University of Copenhagen
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* 18 years or older * Able to understand the Participant Information paper * Diagnosed with hematological cancer * Must be undergoing chemotherapy (at least one treatment during the study) * Outpatient * Be able to take pictures of meals (and send to the sub-investigators) * Be able to speak and read the danish language
Exclusion criteria
* Pacemaker
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Consumption of energy as a percentage of estimated need | 6 weeks | difference - before and after intervention |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Satisfaction (measured with EROTC QLQ-C30 version 3.0) | 6 weeks | difference - before and after intervention. Higher scores means worse outcome. Lower scores means better outcomes. |
| Hand-grip-strength (measured with a dynamometer) | 6 weeks | difference - before and after intervention |
| Fat-free-mass and fat-mass in percent (bioimpedance measurement) | 6 weeks | difference - before and after intervention |
| Protein intake | 6 weeks | difference - before and after intervention |
| Burning/pain in the mouth (measured on a scale) | 6 weeks | difference - before and after intervention measured with Likert scale (1 to 5). Higher scores means a worse outcome. Lower scores means better outcomes. |
| Body weight | 6 weeks | difference - before and after intervention |
Countries
Denmark
Outcome results
None listed