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Opioid Reduction Toolkit Reduces Opioids Prescribed and Consumed

Successful Implementation of an Opioid Reduction Toolkit in Pancreatectomy Patients Significantly Decreases Number of Opioids Prescribed and Consumed

Status
Suspended
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05363436
Enrollment
159
Registered
2022-05-05
Start date
2018-01-01
Completion date
2028-12-31
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid Abuse, Opioid Misuse, Pain

Brief summary

Investigators studied a baseline population of patients receiving pancreatectomies at their institution and determined how many opioid pills each patient was prescribed and how many they took. Based on this data they created a toolkit to provide to prescribers to give patients a modified number of pills. The amount prescribed and consumed was measured after intervention.

Detailed description

A single academic surgical department reviewed opioid treatment patterns for patients undergoing common procedures, including open pancreatectomy, and an opioid reduction toolkit using the data collected was created. Providers were educated on the use of the toolkit and it was implemented as a standard of practice. Data were collected on pancreatectomy patients via telephone interview (performed at 2 weeks post-op) and by reviewing the state prescription drug monitoring program. Outcome variables included morphine milliequivalents (MME) of pills prescribed, MME of pills consumed, number of patients aware of proper unused pill disposal, number of patients requesting refills, and pain scores. Categorical and continuous outcomes were compared within and between groups.

Interventions

DRUGOxycodone

Providers had to prescribe 15 oxycodone pills to each patient discharge

Sponsors

Thomas Jefferson University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Intervention model description

Control group, measurement, intervention group

Eligibility

Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No

Inclusion criteria

* Age \> 18 * Being scheduled for an outpatient elective pancreatectomy

Exclusion criteria

* Urgent/emergent status * Concomitant procedure being performed at time of pancreatectomy

Design outcomes

Primary

MeasureTime frameDescription
Number of opioid pills reported being taken by the patient14 daysPatients will be interviewed fourteen days after procedure and asked how many opioid pills they have taken since being discharged form the hospitals
Number of opioid pills being prescribed14 daysDischarge paperwork and prescription information will be searched to determine the number of opioid pills were provided to the patient at discharge

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026