Antenatal Management of the Fetal Gastrointestinal Atresia
Conditions
Brief summary
Aim- to investigate how prenatal diagnosis of fetal esophageal or intestinal atresia impacts obstetric and neonatal outcomes. Methods- This was a retrospective cohort study at a single center. The study population comprised 51 consecutive pregnancies, including 29 mothers (57%) and their fetuses affected by prenatally diagnosed fetal esophageal or intestinal atresia, and 22 mothers (43%) and their babies with postnatally diagnosed fetal esophageal or intestinal atresia.
Detailed description
Aim- to investigate how prenatal diagnosis of fetal esophageal or intestinal atresia impacts obstetric and neonatal outcomes. Methods- This was a retrospective cohort study at a single center. The study population comprised 51 consecutive participants, including 29 mothers (57%) and their fetuses affected by prenatally diagnosed fetal esophageal or intestinal atresia, and 22 mothers (43%) and their babies with postnatally diagnosed fetal esophageal or intestinal atresia.
Interventions
PROCEDUREscheduled delivery at a tertiary center
Neonatal units in French hospitals are classified in three levels. The intention is for infants requiring high level care to receive it in a tertiary neonatal unit within the same network when appropriate. In case of known fetal gastro-intestinal artesia, the prenatal care includes obstetric consultation and level 3 ultrasound scheduled every four weeks at our unit until the end of the pregnancy, antenatal consultations with a specialized multidisciplinary team, and an antenatal visit of the birth center to reduce the parental anxiety.
Sponsors
Poitiers University Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* all pregnancies affected by fetal esophageal, duodenal or intestinal atresia referred to our prenatal diagnosis unit * all newborns managed for such atresia in our unit of pediatric surgery
Exclusion criteria
* termination of pregnancy, * stillbirth, * the false positive cases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| gestational age of delivery | 1 year | weeks |
| mode of delivery | 1 year | Vaginal, Operative vaginal, Elective cesarean section, Cesarean section for fetal indication |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| neonatal morbidity | 1 year | Age at surgery, Cutaneous stoma, Anastomotic leakage, Mechanical ventilation, Phototherapy, Infection |
| length of hospital stay | 1 year | Length of neonatal intensive care unit stay, Length of neonatal reanimation stay (days) |
Countries
France
Outcome results
None listed