Healthy Aging, Healthy Diet, Healthy Lifestyle
Conditions
Brief summary
To prove the effectiveness of complex wellness programs in terms of maintaining active longevity, including motivational counseling, high-intensity training, intermittent fasting, hypoxic training, as well as practices for achieving healthy sleep and mental well-being. Clinical-instrumental, single-centre, prospective, open-label, non-randomized, sequential enrollment study with blinded endpoint analysis
Interventions
OTHER1. Nutrition; 2. Physical activity; 3. Hypoxic training; 4. Menthal heals improvement
1. Nutrition: intermittent fasting; 2. Physical activity: medium-intensity or high-intensity physical activity; 3. Hypoxic training (at least three per visit to the center); 4. correction of hygiene and sleep duration, relaxation techniques, cognitive behavioral therapy for insomnia. 5. Individual motivational counseling.
Sponsors
Prevent Age Resort Pervaya Liniya
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* Men and women over 18; * No significant (affecting the functional state) active diseases: acute diseases and exacerbations of chronic diseases; * Interest in active longevity and willingness to participate in research. * Signed informed consent.
Exclusion criteria
* Age up to 18 years; * Severe or moderate comorbidities; * Rheumatological (systemic / autoimmune) diseases of any severity; * Intestinal infections (within 3 months); * SARS / pneumonia, other diseases accompanied by systemic inflammation during the last 2 months; * Chronic inflammatory bowel disease; * Major surgery within the last 3 months * Intoxication (alcohol, drugs, other toxins); * Oncological disease (except for basalioma) out of remission; * Persons with mental illness; * Diabetes; * Syndrome of obstructive sleep apnea of moderate and severe severity; * Low adherence to lifestyle interventions, including physical activity of less than 150 minutes of aerobic activity per week (at least two days per week) or 75 minutes of vigorous exercise (at least 3 days per week).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| improved endothelial function | First point: 1 week (2nd visit). Second oint after 6 - 13 months (3rd visit) | improvement of flow-mediated vasodilatation measured by ultrasound (cuff test) |
| improved quality of night sleep | First point: 1 week (2nd visit). Second oint after 6 - 13 months (3rd visit) | improvement in nighttime sleep quality assessed by a Pittsburgh Sleep Quality Scale |
| Reducing the degree of anxiety | First point: 1 week (2nd visit). Second oint after 6 - 13 months (3rd visit) | Reduction in the degree of anxiety according to the assessment of the Spielberger test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| increased self-esteem | First point: 1 week (2nd visit). Second oint after 6 - 13 months (3rd visit) | increasing the level of self-esteem based on the results of the analysis of the Dembo-Rubinstein questionnaire |
| improved quality of night sleep | First point: 1 week (2nd visit). Second oint after 6 - 13 months (3rd visit) | improvement in nighttime sleep quality assessed by a sleep indicator scale |
Countries
Russia
Contacts
Primary ContactAnna Ratnikova
Outcome results
None listed