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Pulmonary Embolism: Mechanism and Therapeutic Innovation

Pulmonary Embolism: Mechanism and Therapeutic Innovation

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05360992
Enrollment
1200
Registered
2022-05-04
Start date
2017-01-01
Completion date
2021-10-13
Last updated
2022-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Embolism

Keywords

pulmonary embolism, chronic thromboembolic pulmonary hypertension, mechanism, therapy, outcome

Brief summary

To explore the pathogenesis, therapy and outcome of pulmonary embolism (PE) and chronic thromboembolic pulmonary hypertension (CTEPH).

Detailed description

The study recruited consecutive outpatients or hospitalized patients diagnosed with pulmonary embolism (PE cohort) and chronic thromboembolic pulmonary hypertension (CTEPH cohort). The follow-up of all patients was performed annually by phone or outpatient visit. The main outcomes were bleeding, recurrent events, and survival. The objective of the study was to explore the pathogenesis, therapy and outcome of PE and CTEPH.

Interventions

None listed

Sponsors

China National Center for Cardiovascular Diseases
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All hospitalized patients or outpatients diagnosed with PE or CTEPH; * Age ≥18.

Exclusion criteria

* Refused informed consents.

Design outcomes

Primary

MeasureTime frameDescription
Recurrent Incidence of Patientsthrough study completion, an average of 1 year.Recurrent PE was measured by computed tomography pulmonary angiography (CTPA) or ventilation/perfusion (V/Q) lung scans. Recurrent deep venous thrombosis was measured by lower extremity Doppler ultrasound.
Bleeding Rate of Patientsthrough study completion, an average of 1 year.Events were recored by follow-up.
Survival Rate of Patientsthrough study completion, an average of 1 year.Events were recored by follow-up.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 11, 2026