Dyspepsia Abdominal Burning Pain Diarrhea Dysentery
Conditions
Keywords
Helicobacter pylori Intestinal Parasites
Brief summary
Intestinal parasitic infections such as Giardia lamblia, Entamoeba histolyica and Enterobius Vermicularis are among the most common infections worldwide.So parasitic infections are considered one of the major health problems in the world especially in developing countries. Helicobacter pylori is a gram-negative,helical-shaped,motile bacillus bacterium,which colonizes the gastric mucosa. H.pylori bacterium secretes urease,a special enzyme that converts urea to ammonia. Ammonia reduces the stomach's acidity .This risk factor allows pathogenic intestinal protozoa such as G.lamblia to take the opportunity to cross through the stomach's increased pH and cause disease.
Interventions
200 stool samples ( 100 positive and 100 negative for H.pylori) after performance of H.pylori stool rapid antigen test then parasitological stool examination will be done
Sponsors
Study design
Eligibility
Inclusion criteria
* patients complaining of dyspepsia , abdominal burning pain,diarrhea,dysentery,of persons of any age or sex group.
Exclusion criteria
* patients taking antibiotics within the previous four weeks, proton pump inhibitors within the previous two weeks, or anti-parasitic drugs within the previous two weeks.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Compare the prevalence of intestinal parasitic infections among positive and negative H.pylori infected outpatients in Sohag University Hospital | 18 weeks following the start point of the study | Collection of 200 stool samples (100 positive and 100 negative for H.pylori) then parasitological examination done for all samples |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Evaluate the prevalence of intestinal parasitic infection among H.pylori infected outpatients in Sohag University Hospital | 18 weeks following the start point of the study | Macroscopic and microscopic examination of 100 positive H.pylori stool samples |
Countries
Egypt