Study of Neutrophils and Circulating Platelets in Correlation With the Activity of T Lymphocytes in Patients With NAFLD (Nonalcoholic Fatty Liver Disease)

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05358496

Acronym

NAFLD

Enrollment

Registered

2022-05-03

Start date

2021-05-03

Completion date

2022-12-30

Last updated

2022-05-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

NAFLD- Non Alcoholic Fatty Liver Disease

Brief summary

The aim of the study is to define the relationship between neutrophils, platelets and the activity of T lymphocytes in patients with NAFLD (nonalcoholic fatty liver disease). This study may predict, in the course of hepatic steatosis, specific phenotypic patterns expressed by PMNs and circulating platelets to evaluate their role in disease progression.

Interventions

DIAGNOSTIC_TESTData collection

Clinical data collection

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients over 18 * No alcoholic abuse * Hepatic steatosis diagnosticated by abdominal ultrasound * Negative hepatitis B and C tests * No history of hepatic cirrhosis

Exclusion criteria

* Under 18 * History of alcoholic abuse * Positive serology for hepatitis B or C * History of hepatic cirrhosis

Design outcomes

Primary

Measure	Time frame
IL-8(interleukin 8)	12 months
Morphology of Circulating Platelets in healthy donors, NAFL, and NASH patients wondering how they may drive and modulate the activity of T cells in this disease	12 months
Platelets count in healthy donors, NAFL, and NASH patients	12 months
number of Neutrophilis	12 months
Morphology of Neutrophilis	12 months

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026