Type 1 Diabetes
Conditions
Keywords
Type 1 Diabetes, blood sugar variations, physical activity
Brief summary
Type 1 diabetes is an autoimmune disease with absence of insulin secretion. Blood sugar is a physiological variable that reflets for blood glucose concentration. Blood sugar level fluctuates, especially during physical activity. Sports activity would increase insulin sensitivity, improve lifestyle and, by extension, promote glycemic balance. However, glycemic balance will be disturbed by physical activity with higher risk of hypoglycemia and hyperglycemia. Moreover, hypoglycemia and hyperglycemia will impact body functions. Perceptions of blood sugar variations during physical exercise and their influences on sports performance have not been studied, whether in type 1 diabetes patients or healthy subjects.
Detailed description
The aim of the study is to evaluate the perception of blood sugar variations in healthy subjects and type 1 diabetes patients during physical activity
Interventions
OTHERPhysical activity
Physical activity: 10 km run on a treadmill
Sponsors
Université de Reims Champagne-Ardenne
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Type 1 diabetics diagnosed more than 3 years ago and controlled (an HbA1c of less than 8%) for type 1 diabetes group * without diabetes for healkthy group * Male * Aged 18 to 65 * Body Mass Index less than 30 kg/m2 * regular running (at least 30 minutes per week and at least one 10-km run per year for the previous 2 years) * Agreeing to participate in the study
Exclusion criteria
* Physical injury * beta blockers treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| blood sugar | Day 0 | Blood sugar evaluated in g/L via continuous blood glucose measurement |
| Feeling lucidity | Day 0 | Lucidity, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between not at all lucid to completely lucid |
| Feeling fatigue | Day 0 | hydratation, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between no feeling of dehydration to dehydrated |
| feeling hungry | Day 0 | hungry, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between no feeling of hunger to hungry |
| average speed per kilometer Sports performance | Day 0 | Sports performance evaluated by average speed per kilometer of the 10 km run on a treadmill |
| total running time | Day 0 | Sports performance evaluated by total running time of the 10 km run on a treadmill |
| average running speed | Day 0 | Sports performance evaluated by average running speed of the 10 km run on a treadmill |
Contacts
Primary ContactPhilippe JOLY, MCU-HDR
Backup ContactCoralie BARBE, MD
Outcome results
None listed