Wound Heal, Periprosthetic Joint Infection
Conditions
Brief summary
In the proposed study, we will apply Prevena on the surgical wound right after closure of the wound in the operating theater. Prevena will be used for 7 days, unless there is ongoing infection or much wound drainage that requires debridement. Most periprosthetic joint infections are from hematogenous origin. Hence, it is considered clean wound unless there is a discharging sinus.
Interventions
We will apply Prevena on the surgical wound right after closure of the wound in the operating theater. Prevena will be used for 7 days, unless there is ongoing infection or much wound drainage that requires debridement.
Sponsors
Chang Gung Memorial Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. patients with periprosthetic joint infection 2. indicated for debridement surgery 3. high risk for wound complication, including one of the followings: diabetes mellitus, use anticoagulants other than aspirin, current smoker, on immunomodulators or steroids, malnutrition, liver disease, renal failure, BMI \> 35 kg/m2
Exclusion criteria
1. previous flap surgery on the indexed joint 2. younger than 18 years of age 3. silver allergy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| wound complication | 12 weeks | Wound complication, including: Persistent wound drainage, blisters, hematoma, wound dehiscence, skin necrosis, suture abscess, cellulitis. |
Countries
Taiwan
Contacts
Primary ContactSheng-Hsun Lee
Outcome results
None listed