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Effects of Combinations of Performance-enhancing Supplements on Exercise Performance

Effects of Different Combinations of Performance-enhancing Supplements on High Intensity Exercise Performance

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05354999
Enrollment
23
Registered
2022-05-02
Start date
2022-04-18
Completion date
2023-12-31
Last updated
2022-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Exercise, Performance, Supplementation

Brief summary

The purpose of the study is to investigate the effect of combinations of creatine monohydrate, sodium bicarbonate and caffeine on exercise performance and fatigability.

Interventions

DIETARY_SUPPLEMENTSodium bicarbonate and caffeine

On experimental days subjects ingest a combination of sodium bicarbonate, caffeine and placebo.

Sponsors

Morten Hostrup, PhD
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy * VO2max of \>50 ml/min/kg for men and \>45 ml/min/kg for women * Performs endurance training \>3 times per week

Exclusion criteria

* Chronic disease deemed by the study responsible medical doctor to interfere with any part of the study * Smoking * Chronic use of prescription medicine deemed by the study responsible medical doctor to interfere with any part of the study

Design outcomes

Primary

MeasureTime frameDescription
Work performed (kJ/Watt)Measured at each trial throughout the study, on average 4 weeksWork performed during a 6 minute time trial

Secondary

MeasureTime frameDescription
Work performed (kJ/Watt)Measured at each trial throughout the study, on average 4 weeksWork performed during a 15 second sprint test
Muscle strength (Nm)Measured at each trial throughout the study, on average 4 weeksMaximal voluntary isometric contraction of m. quadriceps femoris

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026