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Incidence of Postoperative Sore-throat Incidence

Incidence of Postoperative Sore Throat and Risks Analysis in Patients Undergoing General Anesthesia With Endotracheal Intubation: A Prospective Cross-sectional Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05354154
Acronym
InciPost
Enrollment
249
Registered
2022-04-29
Start date
2022-04-01
Completion date
2023-03-31
Last updated
2022-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore-throat

Brief summary

Postoperative sore throat is a distressing but frequent symptom presented by the patients on the floor upon awakening from General Anesthesia, where endotracheal intubation is part of the Anesthetic protocol. Its incidence ranges between 21-71.8%. Good skills and availability of trained staff to cause minimal tissue damage are expected to reduce the incidence. Risks factors associated will be analyzed.

Detailed description

Post-operative sore throat (POST) is a common complication of endotracheal intubation. It ranges from 21 to 71.8 %. Various factors contribute to the development of POST, like, female sex, smoking, intubation difficulty and Suxamethonium use, high endotracheal cuff pressure, airway suctioning, long duration of surgery, mucosal injury with laryngoscopy, or pharyngeal airway use and larger size endotracheal tubes \[9\]. POST has also been associated with laryngeal masks, injury with laryngoscopy, or pharyngeal airway use and larger size endotracheal tubes. Basically it is mucosal damage of the throat and trachea which releases inflammatory mediators and produces soreness. POST leads to postoperative dissatisfaction. Patients of POST are uncontended following general anesthesia. Its preemptive amelioration, has been studied using various pharmacological interventions. The list includes, but is not limited to, Benzydamine hydrochloride (BH), aspirin, ketamine, lidocaine and dexamethasone. There is limited evidence based literature available about the incidence of POST in the investigator's locality in the country. The investigators plan to collect data in General OT of Rehman Medical institute (RMI), Peshawar. The city of Peshawar is the largest city of Khyber Pakhtunkhwa, a province of Pakistan, having a population of approximately 2 million. The objectives of our study is to know the magnitude of the problem and ascertain factors associated with postoperative sore throat among patients undergoing elective surgery under general anesthesia with endotracheal intubation.

Interventions

PROCEDUREendotracheal intubation

Consenting healthy patients of either sex will be endotracheally intubated under controlled environment

Sponsors

Rehman Medical Institute - RMI
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Any patient of either gender aged 18- 60 years * Patients of American Society of Anesthesiologists (ASA) physical status 1 and 2 receiving General Anesthesia with ETT

Exclusion criteria

* Patients having ASA 3 or above physical status * Recent or ongoing Upper Respiratory Tract Infection (URTI) * Patients going to ICU intubated

Design outcomes

Primary

MeasureTime frameDescription
Incidence rate of sorethroatSix hoursIncidence= Those who developed Postoperative sorethroat / All recruited participants who recieve General anesthesia through endotracheal tubes \*100

Secondary

MeasureTime frameDescription
Risk factors assessmentSix hoursAssociated risk factors for postoperative Sore throat will be assessed for presence or absence through a structured performa

Countries

Pakistan

Contacts

Primary ContactMohammad Shafiq, FCPS
mohammad.shafiq@rmi.edu.pk+92-91-5838000
Backup ContactRahman U Jan, MCPS
janrahman21@gmail.com+92-3339749567

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026