Extracorporeal Membrane Oxygenation in Coronavirus Disease (COVID-19), Influenza and ARDS of Other Ethiologies

Extracorporeal Membrane Oxygenation in COVID-19, Influenza and ARDS of Other Ethiologies

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05353725

Enrollment

100

Registered

2022-04-29

Start date

2016-01-01

Completion date

2022-03-01

Last updated

2022-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ARDS, COVID-19, Influenza

Keywords

Extracorporeal Membrane Oxygenation, ARDS, COVID-19, Influenza

Brief summary

A comparison of clinical characteristics and outcomes of patients on extracorporeal membrane oxygenation (ECMO) in COVID-19, influenza and ARDS of other ethiologies

Detailed description

All ARDS patients on extracorporeal membrane oxygenation (ECMO) during January 1st 2016 and January 10th 2022 in University Medical Center Ljubljana were included and their clinical characteristics and outcomes were studied according to ARDS ethiology: COVID-19, influenza and other ethiologies.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient with acute respiratory distress syndrome (ARDS) on extracorporeal membrane oxygenation (ECMO) * 18 years or older

Exclusion criteria

* Patient not eligible for ECMO treatment per institutional guidelines (terminal illness, palliative care)

Design outcomes

Primary

Measure	Time frame	Description
180-day survival	From day of ECMO-implant for every 24 hours until date of death or survival at 180 days	180-day survival from ECMO implantation

Secondary

Measure	Time frame	Description
ICU survival	From day of ICU-admission for every 24 hours until date of death or survival at ICU discharge	ICU survival from ECMO implantation
Hospital survival	From day of hospital admission for every 24 hours until date of death or survival at hospital discharge	Hospital survival from ECMO implantation
Days on ECMO	From day of ECMO-implant for every 24 hours until date of weaning or death	Days on ECMO from ECMO implantation
30-day survival	From day of ECMO-implant for every 24 hours until date of death or survival at 30 days	30-day survival from ECMO implantation
ICU length of stay	From day of ICU-admission for every 24 hours until date of death or date of ICU discharge	ICU length of stay from ECMO implantation
90-day survival	From day of ECMO-implant for every 24 hours until date of death or survival at 90 days	90-day survival from ECMO implantation
Weaning from ECMO	From day of ECMO-implant until date of death or weaning	Weaning from ECMO

Outcome results