Carcinoma, Hepatocellular
Conditions
Keywords
hepatocellular carcinoma, TACE, tumor necrosis
Brief summary
Micronecrosis is a novel pathological feature of hepatocellular carcinoma (HCC). This study was aimed at evaluating the effect of tumor micronecrosis on postoperative transcatheter arterial chemoembolization (TACE) in patients with hepatocellular carcinomas, and further exploring the value of micronecrosis for guiding TACE in HCC management.
Interventions
PROCEDUREtranscatheter arterial chemoembolization
transcatheter arterial chemoembolization after liver resection
Sponsors
Zhejiang University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* (1) pathologically confirmed HCC (2) achievement of R0 resection.
Exclusion criteria
* (1) simultaneous presence of other tumors ; (2) receipt of preoperative anti-tumoral treatments; (3) concurrent treatment with other antitumoral therapies in combination with TACE; (4) tumor necrosis that could be observed by gross examination; (5) a lack of necessary preoperative laboratory test results.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| overall survival | after liver resection until June 1, 2020 | the number of months from the date of surgery to the date of the last follow-up visit or time of death. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| disease-free survival | after liver resection until June 1, 2020 | the number of months from the date of surgery to the date of first confirmable recurrence or death |
Countries
China
Outcome results
None listed