Healthy Diet, Fatty Liver, Insulin Resistance, Metabolic Syndrome, Healthy Lifestyle, Healthy Nutrition
Conditions
Keywords
plant-based, metabolic, fatty-liver
Brief summary
The purpose of this study is to assess the metabolic effects of plant based diet on healthy young adults.
Detailed description
An internet announcement will be made and 60 participants who meet the eligibility requirements will be randomly selected. After being informed about study, all participants (60 omnivores) giving written informed consent will be assigned to the vegan and vegetarian groups of the study according to their preferences, while 20 participants will continue to be omnivores as the control group. At week 0 and 24, blood samples, urine samples, proton density fat fraction MRI evaluations and body composition analyze will be completed.
Interventions
DIETARY_SUPPLEMENTOmnivore
This study will evaluate effects of plant based diets (vegan and vegetarian). 60 omnivore individuals will be included. 20 of the participants will continue their omnivore diet as control group. 20 of the participants will change their diet to vegetarian, and 20 of them will change their diet to vegan.
DIETARY_SUPPLEMENTVegetarian
20 of the participants will change their diet to vegetarian diet. In this group participants will not eat any meat or meat product but can eat/drink milk products, egg and other animal products.
DIETARY_SUPPLEMENTVegan
20 of the participants will change their diet to vegan diet. In this group participants will not eat any kind of animal products.
Sponsors
Koç University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
1. Being 18-40 years old, 2. BMI is 18-30 kg/m2, 3. Having no chronic diseases, 4. Not smoking
Exclusion criteria
1. Having chronic disease, 2. Being older than 40 years old or younger than 18 years old, 3. Smoking, 4. Alcoholism or drinking more than 140 gr/week of alcohol,
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from Baseline Liver Steatosis at 6 months | At week 24 liver steatosis change will be compared between the groups. | Liver steatosis change will be compared between groups at the end of the study. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from Baseline Insulin Resistance at 6 months | At week 24 insulin resistance change will be compared between the groups. | Insulin resistance change will be compared between groups at the end of the study. |
Countries
Turkey (Türkiye)
Outcome results
None listed