Skip to content

Evaluation of Antibiotherapy Prescribed for Outpatients From Emergency Departments

Evaluation of Antibiotherapy Prescribed for Outpatients From Emergency Departments

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05350995
Acronym
EVAPAUR
Enrollment
9600
Registered
2022-04-28
Start date
2022-05-13
Completion date
2023-04-01
Last updated
2022-08-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergencies, Infectious Disease

Brief summary

French health insurance data indicate that approximately 15% of ambulatory antibiotic consumption is generated by hospital prescriptions. This extra-hospital consumption represents a greater volume than intra-hospital consumption. To date, hospital indicators of good antibiotic use do not include this outpatient dimension. This study will provide a snapshot of the proportion of ambulatory antibiotics generated by emergencies and analyze compliance with management recommendations.This study will serve as a basis for developing indicators of outpatient antibiotic consumption generated by hospital activity and for identifying specific intervention targets aimed at the misuse situations that have been highlighted. This study will be carried out in the form of a repeated survey on a given day (4 days, one across each season), carried out by the local mobile antibiotic therapy team, using a standardized grid. The survey will concern all the medical records of the patients visiting any emergency department on the days of the survey. The evaluation of antibiotic therapies prescribed in discharge orders will be carried out in accordance with local management recommendations by the site investigator (infectious disease and/or emergency medicine specialist), who will assess whether the prescription is in accordance with the recommendations or not.

Interventions

OTHERNo intervention

No intervention

Sponsors

Henri Mondor University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Visit on emergency department on one of the survey days * Age ≥18

Exclusion criteria

* Patient opposed to the collection of his/her data * Patient under guardianship or curatorship

Design outcomes

Primary

MeasureTime frameDescription
Adequacy to local or national recommendations of antibiotic prescriptions identified on patient discharge prescriptions after a visit in emergency departments.through study completion, an average of 1 yearAdequacy to local or national recommendations (adequate/not adequate) of prescriptions, assessed by local investigator (infectious disease and/or emergency medicine specialist) at 4 days of collection: 1 day in each season (spring, summer, autumn and winter).

Secondary

MeasureTime frameDescription
Adequacy to the local or national recommendations of the antibiotic prescriptions identified on the patient discharge prescriptions by diagnosis.Through study completion, an average of 1 yearAdequacy to local or national recommendations (adequate/not adequate) of the antibiotic prescriptions identified on the patient discharge prescriptions by diagnosis assessed at 4 days of collection: 1 day in each season (spring, summer, autumn and winter).
Antibiotics prescription rate at discharge from emergency department.Through study completion, an average of 1 year
Critical antibiotics prescription rate at discharge from emergency department.Through study completion, an average of 1 yearCritical antibiotics are defined by ANSM guidelines.
Factors associated with inadequacy to the local or national recommendations.Through study completion, an average of 1 year

Countries

France

Contacts

Primary ContactClément Ourghanlian, PharmD
clement.ourghanlian@aphp.fr0145178029
Backup ContactRaphael Lepeule, MD
raphael.lepeule@aphp.fr0145178003

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026