Pain, Neuropathic
Conditions
Keywords
neuropathy
Brief summary
use of dexmedtemodine to augment analgesia in cases of failed back surgery
Interventions
DRUGHylase plus Triamcinolone plus sterile isotonic saline
transforaminal fluroscopic epidural injection
DRUGHylase plus Dexmedetomidine plus Triamcinolone
transforaminal fluroscopic epidural injection
Sponsors
Minia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
30 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Age group. 25-75ys old * Both sex. * persistent (at least 6 month) pain and or disability following laminectomy with or without sensory-motor neurological deficits or any form of urinary or bowel incontinence * Patients suffering from persistent (\> 6 months) back pain following laminectomy for spinal canal stenosis and/or discectomy for herniated nucleus pulposus documented by magnetic resonance imaging (MRI) were included for screening and enrollment.
Exclusion criteria
* Diabetic patients. * Refusal to participate * MRI with disc sequestration, concurrent sacro-ilitis, facet arthropathy . * Coagulopathic patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pain assesment | 6 months | visual analogue scale |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| functional diability | 6 months | Modified Oswestry Disability Questionnaire....0% to 20%: minimal disability:....21%-40%: moderate disability: 41%-60%: severe disability...61%-80%: crippled |
| acute complications | 6 hours after injection | number of patients developed epidural hematoma by magnetic resonance imaging |
Countries
Egypt
Contacts
Primary Contactmina raouf
Outcome results
None listed