Endometrioma, Endometriosis Ovary, Ruptured Endometrioma
Conditions
Keywords
endometrioma, rupture, endometriosis
Brief summary
Ruptured endometrioma cases were compared with unruptured endometrioma cases.
Detailed description
This study aims to compare the findings in patients who had surgery for ruptured endometrioma with the patients who had an unruptured endometrioma. This study was conducted at Republic of Turkey Ministry of Health, Health Science University Etlik Zübeyde Hanım Gynecology Training and Research Hospital Infertility Clinic and all patients who were operated for endometrioma and had a histopathology report confirming the presence of endometrioma between January 2014 and December 2020 were included. In this study, demographic characteristics, intraoperative findings, laboratory values and follow-up recommendations of two groups compared. The patients' age, presence of sexual activity and/or infertility, gravidity, parity, abortion, history of ectopic pregnancy, accompanying systemic disease, previous operations, drug use, and symptoms were recorded. Preoperative and postoperative complete blood count, Cancer antigen 125 (CA 125), Cancer antigen 19-9 (CA19-9), Cancer antigen 15-3 (CA 15-3), Carcinoembryonic antigen (CEA), alpha fetoprotein (AFP), anti mullerian hormone (AMH), fibrinogen, C-reactive protein (CRP) values of the patients were obtained. Patient files, operation notes and laboratory values of the electronic recording system database and the two groups were compared.
Interventions
PROCEDURELaparoscopy/Laparotomy
All patients included in the study were operated patients.
Sponsors
EZH EAH
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
16 Years to 48 Years
Healthy volunteers
No
Inclusion criteria
* All patients who were operated on in Republic of Turkey Ministry of Health, Health Science University Etlik Zübeyde Hanım Gynecology Training and Research Hospital Infertility Clinic, whose histopathological diagnosis was confirmed as endometrioma, and who did not meet the
Exclusion criteria
, were included in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pre-interventional Comparison of inflammatory parameters | Blood samples were taken from the patients before the surgery | Neutrophil/Lymphocyte ratio (NLR), Platelet/Lymphocyte ratio (PLR), Monocyte/Lymphocyte ratio (MLR) were compared between two groups in the preoperative period |
| Comparison of inflammatory parameters after surgery | Blood samples were taken from the patients in the first postoperative day. | Neutrophil/Lymphocyte ratio (NLR), Platelet/Lymphocyte ratio (PLR), Monocyte/Lymphocyte ratio (MLR) were compared between two groups in the postoperative period |
| Pre-interventional Comparison of tumor markers | Blood samples were taken from the patients before the surgery | Cancer antigens; CA125, CA19-9 and CA 15-3 were compared between two groups in the preoperative period |
| Comparison of tumor markers after surgery | Blood samples were taken from the patients after the surgery up to 24 weeks | Cancer antigens; CA125, CA19-9 and CA 15-3 were compared between two groups in the postoperative period |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sexual activity | Before surgery | The existence of sexual activity in each study group was questioned. |
| Infertility | Before surgery | The existence of infertility in each study group was questioned. |
Countries
Turkey (Türkiye)
Outcome results
None listed