A Postoperative Sore Throat After Lumbar Spine Surgery in the Prone Position

The Effect of Dexmedetomidine and Remifentanil Infusion on Postoperative Sore Throat After Lumbar Spine Surgery in the Prone Position

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05345574

Enrollment

104

Registered

2022-04-26

Start date

2018-12-26

Completion date

2022-12-31

Last updated

2022-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Operative Sore Throat

Brief summary

This study was performed to compare the effect of dexmedetomidine and remifentanil on the incidence and severity of postoperative sore throat in patients undergoing spinal surgery in the prone position who are at risk of developing postoperative sore throat.

Interventions

DRUGdexmedetomidine infusion

dexmedetomidine as anaesthetic adjuvant

DRUGremifentanil infusion

remifentanil as anaesthetic adjuvant

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 65 Years

Healthy volunteers

Inclusion criteria

1. American Society of Anesthesiologists (ASA) physical status classification I and II 2. Undergoing lumbar spine surgery in prone position

Exclusion criteria

1. Pre-existing sore throat, hoarseness, or upper respiratory tract infection 2. Allergy to the study drugs 3. Anticipated difficult airways 4. More than two attempts at intubation

Design outcomes

Primary

Measure	Time frame	Description
incidence of postoperative sore throat at rest	1 hour after surgery	0=none; 1=occur
incidence of postoperative sore throat at swallowing	1 hour after surgery	0=none; 1=occur
severity of postoperative sore throat at rest	1 hour after surgery	4-point scale (0=none; 1=mild; 2=moderate; 3=severe)
severity of postoperative sore throat at swallowing	1 hour after surgery	4-point scale (0=none; 1=mild; 2=moderate; 3=severe)

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026