MRI, Osteoarthrosis
Conditions
Keywords
MRI, Osteoarthrosis
Brief summary
This clinical trial studies the use of 7-Tesla (7T)and 3T magnetic resonance imaging (MRI) in detecting osteoarthrosis. 7T MRI has increased detection sensitivity, including more accurate lesion delineation, higher inter-rater agreement. Diagnostic procedures such as 7T MRI may help ultimately improved diagnostic and therapies confidence to inform decision making than standard 3T MRI.
Detailed description
7T MRI increased detection sensitivity, attain superior anatomic resolution, higher spatial and spectral specificity of advanced quantitative techniques, and shorter scan times than 3T MRI. When applied clinically, these benefits translate to increased detection sensitivity, and ultimately improved diagnostic and therapies confidence to inform decision making. This study aim to detect the image characteristics and diagnostic accuracy of osteoarthrosis on 7T MRI.
Interventions
DIAGNOSTIC_TESTMagnetic resonance imaging
Patients recruited will receive Magnetic resonance imaging.
Sponsors
Chinese PLA General Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Age≥18 and ≤80 * Having no contraindications against MRI * Clinically stable
Exclusion criteria
* Age#18 or #80 * Pregnancy and other contraindication to MRI scan * Informed consent not obtained
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The thickness of the cartilage of patellar on 7T MRI scan | baseline | Thickness of different part of the cartilage of patellar measured based on axial PD images |
| The T2 mapping value of the patellar cartilage on 7T MRI scan | baseline | T2 relaxation times of the patellar cartilage measured based on T2 mapping |
| The abnormal signal in the infrapatellar fat pad | baseline | The exist of abnormal signal in the infrapatellar fat pad detected based on sagittal PD images |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Signal change of the patellar chondral before and after rehabilitation | 1 month after rehabilitation | The correlation between abnormal change of the patellar chondral and reaction 1 month after rehabilitation |
| Signal change of the infrapatellar fat pad before and after rehabilitation | 1 month after rehabilitation | The correlation between abnormal signal in the infrapatellar fat pad and reaction 1 month after rehabilitation |
Countries
China
Contacts
Primary ContactJiayu Huang, M.S.
Outcome results
None listed