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Two Time a Week vs. Five Time a Week Blood Flow Restriction Training Program for the Lower Extremity.

Blood Flow Restriction Training for the Quad: Comparing Daily Training vs. Training Twice a Week

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05342909
Enrollment
55
Registered
2022-04-25
Start date
2020-09-01
Completion date
2022-06-30
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Flow Restriction Training

Brief summary

This study will randomize healthy adults who regularly perform resistance training exercises for the lower extremities (2x a week) to one of three groups: a blood flow restriction (BFR) exercise group that trains 2x a week, a BFR exercise group that trains 5x a week, and a control group that does not perform any additional BFR exercise. Those randomized to the BFR groups will perform the unilateral 90-0 knee extension exercise followed by the bilateral squat. Subjects will have the BFR applied to their dominant lower extremity and will perform 4 sets (30/15/15/15 reps) per exercise. Training will initial start at 30% of 1RM with training intensity increased by 5% every 2 weeks. The training program will last 8 weeks. Pre- and posttests include ultrasound imaging of the dominant leg rectus femoris and strength testing via hand held dynamometry.

Interventions

OTHER5x a week BFR training group

This group will perform the two exercises 5x a week with blood flow restriction, set to 80% of limb occlusion pressure, applied to the dominant thigh.

OTHER2x a week BFR training group

This group will perform the two exercises 2x a week with blood flow restriction, set to 80% of limb occlusion pressure, applied to the dominant thigh.

Sponsors

George Fox University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Masking description

The outcomes assessors are blinded to group allocation.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

healthy adults 18 years of age who currently perform weight-lifting (i.e., resistance training) exercise 2x a week. \-

Exclusion criteria

current musculoskeletal injury; surgery to the low back or lower extremities during the prior year; one or more contraindications to blood flow restriction training. \-

Design outcomes

Primary

MeasureTime frameDescription
Muscular strength8 weeksHand held dynamometry will be used to assess changes in strength (bilaterally) for the quadricep, hip extensors, and hip abductors.
Cross-sectional area of the rectus femoris8 weeksUltrasound imaging will measure the cross-sectional area of the rectus femoris

Countries

United States

Contacts

Primary ContactJason Brumitt, PhD
jbrumitt@georgefox.edu5035542461

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026