Precision Nutrition

Nutrient Deficiency

Genotypes, Nutrient intakes, Nutrient plasma levels

Determine the relationship between relevant genotypes and nutrient plasma levels, with the aim to normalize such levels using a nutritional intervention. (Original text in Romanian language: Caracterizarea precisa a relatiei dintre variatiile genetice si nivelul de nutrienti din sange/plasma/ser, in scopul de a defini modul in care aportul alimentar poate normaliza aceste nivele.)

1. Define plasma levels prediction formulas for each involved nutrient, based on relevant genotypes; 2. Characterize the roles that food intakes may have in the alteriations of such plasma levels, depending on genotype structure; 3. Based on clinical data, create predictive equations using dependent variables (genotypes) in order to define optima nutrient intakes; 4. (Secondary aim): compare the efficacy of a nutrigenetic-based intervention with a non-nutrigenetic intervention (classical approach). (Original text in Romanian language: 1. Definirea unor formule de predictie a nivelelor din sange, in functie de variatiile genetice; 2. Caracterizarea rolului pe care aportul alimentar de nutrienti il are in modularea acestor valori, in contextul variatiilor genetice. 3. Gasirea unor formule de predictie in care variabilele independente (variatii genetice si combinatii ale acestora) sa defineasca necesarul de nutrienti pentru a normaliza valorile sangvine ale acestor nutrienti. 4. (Obiectiv secundar): compararea eficacitatii unei interventii nutrigenetice fata de o interventie clasica nutritionala (non-nutrigenetica).)

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