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Effects of Exercise Intervention on Muscle Strength in Severely Ill Patients

Effects of Exercise Intervention on Muscle Strength in Severely Ill Patients

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05342129
Enrollment
60
Registered
2022-04-22
Start date
2020-07-17
Completion date
2022-03-01
Last updated
2022-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intensive Care Unit Patients

Keywords

Intensive care unit patients, exercise Training

Brief summary

In recent years, due to the improvement in the survival rate of the intensive care unit, the problem of severe systemic fatigue (Intensive care unit acquired weakness; ICUAW) has continued to receive attention. Muscle mass decreases by 3-11% within a week, resulting in decreased muscle strength and muscle atrophy. Current studies suggest that ICUAW can lead to poorer function, prolonged ICU stay, and decreased quality of life. This study aimed to understand the muscle strength of critically ill patients and to explore the effect of exercise intervention on improving muscle strength. The experimental group received a four-week exercise bike intervention plus conventional rehabilitation exercises, while the control group received conventional rehabilitation exercises.

Detailed description

The content of the exercise is to use an exercise bike, start pedaling on the first day, time setting: 20 minutes, speed: 2, and adopt passive mode. If you can complete the exercise on the first day, the time will be adjusted to 30 minutes on the second day. If you cannot complete the exercise on the first day, the time will still start from 20 minutes on the second day. The maximum time is 30 minutes. If you can complete 30 minutes of passive exercise for 3 consecutive days, the fourth day will be adjusted to active exercise. The entire exercise training is seven days a week, once a day, once a 30-minute, at least 5 days. Those who were discharged to the general ward continued to complete this exercise training for up to 28 days. Stop exercising if heartbeat \> 140, mean arterial pressure \< 65, blood oxygen \< 90%, respiration \> 35 beats/min, or the patient requests to stop during exercise.

Interventions

OTHERexercise bike

exercise is to use an exercise bike, start pedaling on the first day, time setting: 20 minutes, speed: 2, and adopt passive mode. If you can complete the exercise on the first day, the time will be adjusted to 30 minutes on the second day. If you cannot complete the exercise on the first day, the time will still start from 20 minutes on the second day. The maximum time is 30 minutes. If you can complete 30 minutes of passive exercise for 3 consecutive days, the fourth day will be adjusted to active exercise. The entire exercise training is seven days a week, once a day, once a 30-minute, at least 5 days. Those who were discharged to the general ward continued to complete this exercise training for up to 28 days.

Sponsors

Taipei Veterans General Hospital, Taiwan
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

1. Aged over 20 years old 2. Conscious 3. willing to participate in this study, and signed the consent form 4. no lower extremity activity taboo, and can walk independently before admission

Exclusion criteria

1. Have neuromuscular disease. 2. Unable to step on a bed bike.

Design outcomes

Primary

MeasureTime frameDescription
The daily observation record sheet includesup to 28 daysVital signs,respirator is used or not,bicycle use pattern,speed and time,reasons for stopping
total days in hospitalbaselineHealth Assessment Form
body mass indexbaselineHealth Assessment Form
level of albuminbaselineHealth Assessment Form
Basic Demographic Health Assessment FormbaselineAge, sex, diagnosis, disease severity, reason for ICU admission
days in intensive care unitbaselineHealth Assessment Form
days on ventilatorbaselineHealth Assessment Form

Secondary

MeasureTime frameDescription
foot liftbaseline(T0)Use a tape to measure foot lift
walking distance in 6 minutesbaseline(T0)Measure 6-minute walking distance
Hand grip strengthbaseline(T0)Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026