Ards, Extracorporeal Membrane Oxygenation, Mechanical Ventilation Pressure High
Conditions
Brief summary
Mortality of patients with COVID-19 associated acute respiratory distress syndrome (CARDS) treated with veno-venous extra-corporal membrane oxygenation (vv-ECMO) is increasing over time since the beginning of the COVID-19 pandemic. The objectives were to retrospectively describe over the first ten days after vv-ECMO implantation, the ventilatory management of CARDS and to assess the impact of static respiratory system compliance (CRS) on the first day of vv-ECMO on 180-day mortality.
Interventions
OTHERNo applicable
No applicable
Sponsors
Central Hospital, Nancy, France
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with ARDS secondary to COVID-19 pneumonia requiring ECMO-VV support, hospitalized in the intensive care units of the CHRU of Nancy, Marseille or Bordeaux between 01/03/2020 and 31/12/2021. * Age \> 18 years old
Exclusion criteria
* Respiratory parameters not available on ten first day of VV ECMO implantation. * Patient refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vital status (dead or alive) | Days, 10. | according to compliance during the first ten days of VV ECMO implantation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Evolution of driving pressure | Days, 10 | after VV-ECMO implantation |
| Evolution of tidal volume | Days, 10 | after VV-ECMO implantation |
| Evolution of PEEP | days, 10 | after VV-ECMO implantation |
Countries
France
Outcome results
None listed