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Trajectories of Resilience and Bariatric Surgery Outcomes

Resilience Trajectories Following a Preoperative Lifestyle /Behavioral Modification Program and Bariatric Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05341414
Acronym
ECLAIRCIE
Enrollment
200
Registered
2022-04-22
Start date
2021-05-03
Completion date
2021-12-15
Last updated
2022-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bariatric Surgery Candidate, Psychological Distress, Severe Obesity

Keywords

Severe obesity, Resilience, Trauma, Psychological disorders, Eating disorders, Bariatric surgery

Brief summary

A high prevalence of psychological trauma on one hand and of psychiatric disorders, such as depression, anxiety, suicide attempts, addictions, and eating disorders on the other hand, has been reported in patients with severe obesity seeking bariatric surgery. Some studies reported an increased prevalence of these psychiatric disorders after bariatric surgery, potentially related to weight regain. In this context, psychological resilience is a concept that brings together internal and external factors of adaptation, and whose clinical use facilitates interdisciplinary collaborative work. This research focuses on the association between resilience and success or failure of bariatric surgery in patients followed in the Specialized Obesity Center (CSO) of the Nancy University Hospital. The hypothesis is that psychological resilience before surgery promotes successful surgical treatment. This retrospective study is based on existing data from patients with severe obesity who have undergone bariatric surgery at the Nancy CSO. The main objective is to study 1) the resilience of patients with severe obesity, candidates for bariatric surgery, at the first assessment (T0), at the end of lifestyle/behavioral modifications program (T1) and at 2 years after bariatric surgery (T2), 2) the relationship between internal and external factors explaining resilience and final weight outcomes. The investigators are expected that non-resilient patients have more psychological vulnerabilities (psychopathology, negative life events, etc.), and have lower weight loss than resilient patients.

Detailed description

The investigators will report the change of resilience during lifestyle/behavioral modifications program and 2 years after bariatric surgical treatment, and the investigators will describe the factors associated with this change: * History of trauma * Psychopathology (eating disorders, depression, anxiety, addiction) * Personality factors * Characteristic of psychotherapy

Interventions

None listed

Sponsors

Central Hospital, Nancy, France
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Severe obesity (BMI ≥35 kg/m2) * Candidate for Bariatric surgery at Nancy CSO (2016-2020) after a lifestyle/behavioral modifications program * Full psychological assessment data

Exclusion criteria

* Patient's opposition to the use of data for research purposes

Design outcomes

Primary

MeasureTime frameDescription
Resilience (Questionnaire) : Resilience Scale for Adult (RSA)baseline (T0)Min: 33 ; Max: 231; Higher scores mean a better outcome Score of resilience (Resilience Scale for adults) and level of resilience (non-resilient, intermediate, resilient) / number of patients in each category
Resilience (semi-structured interview) : level of resiliencebaseline (T0)Categories : Non-resilient, intermediate, resilient Number and % of patients in each category

Secondary

MeasureTime frameDescription
Binge eating scale (BES)baseline (T0)Min: 0 ; Max: 48 ; Higher scores mean a worse outcome.
Mini International Neuropsychiatric Interview (semi-structured interview)baseline (T0)Number and % of patients in each category (major depressive episode, dysthymia, suicidal risk, bipolar disorder, panic disorder, agoraphobia, social phobia, obsessive compulsive disorder, post-traumatic stress disorders, alcohol (addiction/abuse), drugs (addiction/abuse), psychotic disorders, generalized anxiety, anti- social personality disorders, eating disorders).
Psychological trauma (semi-structured interview)Baseline (T0)Number and % of patients in each category (Sexual, physical, emotional abuse, emotional and physical neglect) Number and % of patients in each category for the first trauma (childhood, adolescence, adulthood)
Childhood Trauma Questionnaire (CTQ)baseline (T0)Min: 25 ; Max: 125 ; Higher scores mean a worse outcome
Toronto Alexithymia Scale (TAS)baseline (T0)Min: 20 ; Max: 100 ; Higher scores mean a worse outcome
Medical Outcomes Study Short Form (SF-36)baseline (T0)Min: 0 ; Max: 100 ; Higher scores mean a better outcome.
Definition of patient's psychological profile : clinical interviewsbaseline (T0)Profile is determined by clinical interviews
Definition of patient's psychological profile : Rorschach testbaseline (T0)Profile is determined by Rorschach test
Characteristics of psychotherapy : Durationbaseline (T0)Duration of psychotherapy (month)
Characteristics of psychotherapy : Frequencybaseline (T0)Frequency of psychotherapy (number of sessions per month)
Characteristics of psychotherapy: Type of professionalbaseline (T0)Type of professional (Psychiatrist, Psychologist, Nurse, Other)
Hospital Anxiety and Depression scale (HAD)baseline (T0)Min: 0 ; Max: 42; Higher scores mean a worse outcome.
Sexbaseline (T0)men/women
Agebaseline (T0)years
Professional situationbaseline (T0)Active / Unemployed / Homemaker / Retired / Unable to work
Family situationbaseline (T0)Currently married/cohabiting / Formerly married / Never married
Weight databaseline (T0)Weight: kg BMI: kg/m²
Mini International Neuropsychiatric Interview10 months (T1)• Number and % of patients in each category (major depressive episode, dysthymia, suicidal risk, bipolar disorder, panic disorder, agoraphobia, social phobia, obsessive compulsive disorder, post-traumatic stress disorders, alcohol (addiction/abuse), drugs (addiction/abuse), psychotic disorders, generalized anxiety, anti- social personality disorders, eating disorders).
Definition of patient's psychological profile :clinical interviews10 months (T1)Profile is determined by clinical interviews
Characteristics of psychotherapy: Duration10 months (T1)Duration of psychotherapy (month)
Characteristics of psychotherapy: Frequency10 months (T1)Frequency of psychotherapy (number of sessions per month)
Characteristics of psychotherapy: Investment10 months (T1)Investment in psychotherapy (0:bad ; 5: excellent) Min: 0 ; Max: 5 ; Higher scores mean a better outcome.
Characteristics of psychotherapy : Investmentbaseline (T0)Investment in psychotherapy (0:bad ; 5: excellent) Min: 0 ; Max: 5 ; Higher scores mean a better outcome.
Dutch Eating Behaviour Questionnaire (DEBQ)baseline (T0)Min: 33 ; Max: 165 ; Higher scores mean a worse outcome

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026