Graphene Oxide in the Surgical Management of Intrabony Periodontal Defects

Graphene Oxide in the Surgical Management of Intrabony Periodontal Defects: A Randomized Experimental Study With Histomorphometric Analysis

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05341245

Enrollment

Registered

2022-04-22

Start date

2022-05-01

Completion date

2023-06-01

Last updated

2022-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal Diseases

Brief summary

Using Graphene oxide in the surgical management of periodontal intrabony defects.

Detailed description

Evaluation of the effect of Graphene oxide in the surgical management of periodontal intrabony defects in animals in periodontal clinical parameters with histomorphometric evaluation .

Interventions

PROCEDUREGraphene oxide and open flap debridement

Using Graphene oxide with open flap debridement in management of periodontal intrabony defects in dogs

PROCEDUREOpen flap debridement

Using Open flap debridement in management of periodontal intrabony defects in dogs

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

1 Years to 2 Years

Healthy volunteers

Inclusion criteria

* male dogs * 12-24 months old with approximate weight of 20-30 kg and general good health will be used

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
periodontal probing depth	2 months	To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects regarding the changes in periodontal probing depth measured in mm using University of North Carolina periodontal probe( UNC 15 probe ).
Clinical attachment level	2 month	To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects regarding the changes in clinical attachment level measured in mm using University of North Carolina periodontal probe( UNC 15 probe )

Secondary

Measure	Time frame	Description
Histomorphometric evaluation	2 months	To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects using histological sections obtained from the surgical site to do quantitative assessment of bone remodeling, modeling, and structure by counting the number of osteoblasts and the number of bone trabeculae using computer based microscope and software.

Contacts

Primary ContactZeiad Rashad

Zeiadkhaled2010@gmail.com2001111309030

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026