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The Prevalence and Risk Factors of Irritable Bowel Syndrome Among Adults

The Prevalence and Risk Factors of Irritable Bowel Syndrome Among Adults: A Multi-Centre Cross-sectional Study.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05340400
Enrollment
5500
Registered
2022-04-22
Start date
2022-04-25
Completion date
2022-06-10
Last updated
2022-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colonic Diseases, Functional, Irritable Bowel Syndrome

Keywords

Rome IV criteria, Colonic Diseases, Digestive System Diseases, Irritable Bowel Syndrome

Brief summary

This is a multicenter cross-sectional study on the prevalence of Irritable Bowel Syndrome and the risk factors associated with it. The Rome IV criteria is used for diagnosing IBS. A questionnaire-guided interview will be applied to all subjects.

Detailed description

: Irritable Bowel Syndrome (IBS) is a common functional bowel disorder characterized by abdominal pain or discomfort associated with defecation or an altered bowel habit. IBS can be divided into four subtypes according to the predominant bowel pattern: diarrhea-predominant (IBS-D), constipation-predominant (IBS-C), and both diarrhea and constipation (IBS-M), and when a stool pattern cannot be categorized under any of the above three patterns (IBS-U). For clinicians, diagnosis of IBS can be challenging because symptoms can be variable over time, and what makes it a real challenge is the absence of a gold diagnostic standard for this syndrome. That is why experts developed the Rome criteria in 2006, which is constantly revised. The latest update of these criteria was published in 2016 as Rome IV. Unfortunately, studies have indicated higher rates of psychological comorbidity including suicidal ideation and depression among IBS patients, and a significant reduction in health-related quality of life, this negatively affects the productivity of the individual in society. Epidemiological studies of this syndrome have indicated a greater prevalence among women than men, and adolescents among other age groups. However, despite these attempts by researchers to determine the prevalence patterns and risk factors for this syndrome, many of them are still not sufficiently defined. Hence, our study came to determine the prevalence and risk factors of Irritable Bowel Syndrome among adults.

Interventions

OTHERROME IV Criteria

Collaborators will use Rome IV criteria for diagnosing IBS by the presence of the abdominal pain at least once a week in the last 3 months, in addition to at least two of the following: abdominal pain related to defecation, change in stool frequency, or shape.

Sponsors

University of Aleppo
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Volunteer to participate in the study

Exclusion criteria

* Poorly-controlled hyperthyroidism * Poorly-controlled hypothyroidism * Poorly-controlled hyperparathyroidism * Liver disease * Paralysis * Parasitic diseases (worms ...) * Celiac disease * Inflammatory bowel disease (Crohn's disease or Ulcerative colitis) * Lactose intolerance * Cancer or tumor in the digestive tract

Design outcomes

Primary

MeasureTime frameDescription
The Prevalence of Irritable Bowel Syndrome30 daysCollaborators will make an interview questions using ROME IV to diagnose IBS among adults.

Secondary

MeasureTime frameDescription
Physical activity as risk factor for IBS30 daysCollaborators will use the World Health Organization questionnaire to classify the physical activity of the participants into good and poor physical activity.
Perceived Stress Scale as risk factor for IBS30 daysIt is the most widely used measure of global perceived stress, and a robust predictor of health and disease. The total score is calculated on the basis of the answers to a series of questions based on monthly stress, and the participant's health status. PSS is a summary measure of ten items (range 0-4 points for every item). It is classified into low (PSS 0-13), moderate (PSS 14-26), and high perceived stress (PSS 27-40).
Fatigue as risk factor for IBS30 daysFatigue will be measured using the Chalder Fatigue Scale (CFQ), a self-administered questionnaire for measuring the extent and severity of fatigue within both clinical and non-clinical, epidemiological populations. CFQ is a summary measure of eleven items (range 0-33)
Diet and weight questions as risk factor for IBS30 daysCollaborators will use a questionnaire to determine the participant's predominant dietary pattern, feeding patterns and allergies
Habits as risk factor for IBS30 daysSmoking, drinking alcohol, caffeine intake, and sleep pattern.

Countries

Syria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 8, 2026