Short-term Automated Longitudinal Analysis of Speech and Language in Cognitive Impairment

"Análisis Longitudinal Del Habla y Seguimiento a Corto Plazo de Las Facultades Cognitivas de Personas Mediante Una Serie de Pruebas: Lista de Palabras CERAD, Repite Los dígitos en Orden Inverso, TMTA-B, Prueba Del Reloj, Fluidez fonémica, comprensión Verbal Relaciones semánticas, y semánticas Alternas".

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05340218

Enrollment

196

Registered

2022-04-22

Start date

2019-01-01

Completion date

2022-03-22

Last updated

2026-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementia, Mild Cognitive Impairment

Brief summary

Validate speech analysis AI models: * To contrast the accuracy of acceXible's platform as a screening tool in the detection of people with cognitive impairment and mild dementia. * To evaluate the correlation between automatically analyzed linguistic variables and a combination of standard measures of cognition. * To assess short-term variability in language ability among older adults, and to assess which aspects of language vary during the study period.

Interventions

OTHERSpeech analysis

Speech analysis to detect and monitor mild cognitive impairment

Study design

Allocation

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

55 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* Adult patients 55+ years of age with suspected MCI or diagnosis of dementia and obtains a score greater than 20 on the MMSE. * Patients must have agreed to participate in the study and have voluntarily signed the informed consent. * (Healthy) Participants without a diagnosis neurological, or psychiatric disorders. Or taking medication that can affect cognitive abilities.

Exclusion criteria

* To have received a diagnosis of a significant psychiatric disorder or other cognitive impairment not due to neurodegeneration. * To have significant vision problems that would affect the ability to perceive visual stimuli. * To have significant hearing problems that would affect the ability to understand verbal cues.

Design outcomes

Primary

Measure	Time frame	Description
Pre-post variability of normal, MCI and dementia at both points of the study.	Change from the baseline cognitive function at 9 months.	Through standard deviation of normal subjects, MCI and dementia, variations in language are measured by considering MMSE scores and the most significant variables of accexible's tests (image description test, phonetic verbal fluency test and semantic verbal fluency test).

Secondary

Measure	Time frame	Description
Correlation between cognitive tests and language variables obtained by the platform.	Every 6 to 9 months	Correlation between: Standard measures of cognition (e.g., MMSE score) + behavioral and psychiatric symptoms of mild cognitive impairment and language.

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 26, 2026