Knee Osteoarthritis
Conditions
Brief summary
Knee osteoarthritis is one of the most common causes of pain and loss of function in the elderly population and is a source of socioeconomic costs. Selective denervation of the superior medial, superior lateral and inferior medial genicular nerves, which provide the sensory innervation of the knee joint, is an effective treatment method used to relieve pain and improve functional capacity. Radiofrequency neurolysis of genicular nerves (RFN) is accepted as an effective technique for the treatment of knee pain. However, due to higher equipment costs, longer procedure times, and procedure-related pain, alternative treatments are needed.
Interventions
PROCEDUREGenicular nerve radiofrequency neurolysis
Neurolysis of superomedial, superolateral and inferomedial genicular nerves
PROCEDUREGenicular nerve chemical neurolysis
Neurolysis of superomedial, superolateral and inferomedial genicular nerves
Sponsors
Diskapi Teaching and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\-
Exclusion criteria
* Coagulation disorders * Rheumatoid disorders * Infections
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Numerical Rating Scale (NRS) | Change from baseline to 6 months after procedure | Pain Score Change The 11-point NRS consists of numbers between 0 and 10 where 0 indicates no pain and 10 indicates maximum pain. The patient is instructed to identify one number between 0 and 10, which is best representative of their pain intensity. |
Countries
Turkey (Türkiye)
Outcome results
None listed