Atrial Fibrillation, Frailty, Major Bleed
Conditions
Keywords
Atrial Fibrillation, Frailty, Major Bleed, Intra cranial Haemorrhage, Cognitive disorder, eHealth
Brief summary
Geriatric patients are at high risk of cardiovascular complications, and for the development of atrial fibrillation. Often atrial fibrillation exists in these patients without specific symptoms, and could therefore remain unknown. Furthermore, concerns exist about the bleeding profile of anticoagulation in the very elderly or frail patients. This study applies opportunistic screening for atrial fibrillation as advised in the latest ESC Guideline on the diagnosis and management of atrial fibrillation. Furthermore, multiple bleeding risk scores will be applies, to better assess the bleeding risk in very elderly or frail patients.
Interventions
DEVICEHeartSDK
The photoplethysmography (PPG) application enables patients to perform a finger tip heartbeat measurement and automatic analysis
Sponsors
Dijklander Ziekenhuis
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
All newly referred patients of 65 years and older that visit geriatric outpatient services are eligible (including Fall clinic, Memory clinic, Pre-operative geriatric assessment clinic, or any other geriatric outpatient clinics that are led by a geriatrician).
Exclusion criteria
* The patient has a pacemaker or implantable cardioverter defibrillator. * The patient is known with a severe dementia, MoCA ≤ 15 points. * The patient has a severe tremor, from whatever cause, and thus is unable to use the PPG based smartphone AF detection algorithm.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Newly identified cases of atrial fibrillation | The first 6 months after recruitment for the study | PPG or ECG detected new cases of atrial fibrillation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Major bleeding | From recruitment until 3 years after the recruitment of the last participant | Major bleeding, including intra cranial haemorrhage |
| Stroke | From recruitment until 3 years after the recruitment of the last participant | Stroke |
| Death | From recruitment until 3 years after the recruitment of the last participant | Death |
| Cognitive disorder | From recruitment until 3 years after the recruitment of the last participant | Development of dementia, categorized by aetiology, during follow up |
| New Atrial Fibrillation, developed after the screening period | From recruitment until 3 years after the recruitment of the last participant | New Atrial Fibrillation, developed after the screening period |
Countries
Netherlands
Outcome results
None listed