Post Partum Haemorrhage
Conditions
Keywords
Post partum haemorrhage, Bleeding, Labour, Vaginal delivery, Caesarean section
Brief summary
Post partum haemorrhage is a concerning situation in maternity wards, though it is not the first cause of maternal mortality anymore. It has been already shown that low fibrinogen level is a major predictive factor of massive bleeding after delivery. In this situation, the early knowledge of fibrinogen level could enhance care of women experiencing post partum haemorrhage. In a cohort of women suffering from post partum haemorrhage, this study will evaluate whether assessing fibrinogen level would be faster using the Quantra® system than the standard coagulation test.
Interventions
None listed
Sponsors
University Hospital, Montpellier
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Women ≥ 18 years old Experiencing post partum haemorrhage ≥ 500 mL Within 24 hours after delivery
Exclusion criteria
* Previous anemia ≤ 7g/dL * Known bleeding disorders * Ongoing antiplatelets treatment * Ongoing anticoagulant treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of delay in obtaining Quantra Fibrinogen Clot Stiffness result to standard fibrinogen level result | When post partum haemorrhage occurred, within 24 hours after delivery | Comparison of delay in obtaining Quantra Fibrinogen Clot Stiffness result to standard fibrinogen level result |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of level of fibrinogen assessed by Quantra Fibrinogen Clot Stiffness to level of fibrinogen assessed by standard coagulation test | When post partum haemorrhage occurred, within 24 hours after delivery | Fibrinogen level assessed by Quantra and standard coagulation tests |
| Comparison of Quantra Clot Time result to Standard Kaolin Clotting time result | When post partum haemorrhage occurred, within 24 hours after delivery | Coagulation function assessed by Quantra and standard coagulation tests |
| Comparison of Platelet Clot Stiffness result to standard platelet count result | When post partum haemorrhage occurred, within 24 hours after delivery | Platelet function assessed by Quantra and standard platelet count. |
| Rate of satisfaction of anesthetist in charge of patient assessed by Lickert scale | When post partum haemorrhage occurred, within 24 hours after delivery | Rate of satisfaction of anesthetist in charge of patient assessed by Lickert scale \[1-Strongly disagree ; 2-Disagree ; 3-Neither agree nor disagree ; 4-Agree ; 5-Strongly agree |
Contacts
Primary ContactJessie Grenié, MD
Outcome results
None listed