Evaluation of Lesion Sterilization and Tissue Repair Techniques Versus Pulpectomy in Primary Molars With Inflammed Pulp

Pulpitis - Irreversible

LSTR, Lesion Sterilization and Tissue Repair, pulpectomy, zinc oxide and eugenol, irreversible pulpitis, vital, primary molars

Group I (Experimental group I): Lesion Sterilization and Tissue Repair with radicular instrumentation. Coronal and accessible radicular pulp tissue are extirpated using rotary files. After proper drying, the paste is placed in the cavity and canals. Group II (Experimental group II): Lesion Sterilization and Tissue Repair with no radicular instrumentation. Only the coronal pulp is removed, the pulpal floor is covered with triple antibiotic paste with propylene glycol mix. Group III (Control group): Conventional pulpectomy. Pulp tissue extirpation is done. Biomechanical preparation is done using rotary files with frequent irrigation with Chlorhexidine. The canals are dried using sterile absorbent paper points followed by obturation by the paste of Zinc oxide and eugenol.

The principal investigator will carry out all treatment procedures, and the patients will be assigned into three groups. For the three interventions "Two test arms and one control group": 1. Diagnostic chart with personal, medical and dental history will be filled. 2. Clinical examination will be performed to assess the clinical inclusion criteria. 3. Preoperative radiographs will be taken to assess the inclusion criteria. Preoperative radiograph will serve as a reference for the follow-up radiographs. 4. Informed consent is taken from participating parents, and they are asked to attend follow-up meetings every 3 month or whenever there is any symptom. 5. Baseline records (personal data collection, photographs, percussion test and preoperative periapical radiographs). 6. Allocation (concealed by withdrawing a sealed opaque envelope containing eight times folded paper containing the intervention that will be used then writing patient name and I.D. on it and will be opened after performing the access cavity). 7. Administration of Ibuprofen in age-dosage volume before administration of local anesthesia by 30 minutes to decrease pulpal pain, pain of injection and post-operative pain. 8. Administration of local anesthesia at the side of the affected molar. 9. Application of rubber dam for isolation, then a standardized pulpotomy procedure will be performed using a large sterile round end bur in a high-speed handpiece with copious irrigation followed by irrigation with 2% Chlorhexidine gluconate. Ethylenediaminetetraacetic acid "EDTA" will be used to remove the smear layer leading to clean and patented dentinal tubules. 10. Children will then be allocated into either one of the groups alternatively depending on the technique of intervention by opening a closed white envelope that is drawn for the patient. Preparation of triple antibiotic paste: The commercially available antibiotics are taken in separate dappen dishes. The enteric coating of the tablet is removed by scraping the coating with a blade, and for the capsule the outer capsular material is removed. Then each of the components is powdered separately with a clean mortar and pestle. Care should be taken to avoid wetting of powder. At this stage, the powder can be stored separately in tightly capped containers in a dark place or in the refrigerator to prevent exposure to light and moisture. After proper pulverization, each of the components is taken in a clean glass slab/mixing pad. Then a part of propylene glycol as a solvent is dispensed and mixed with equal parts of antibiotics powder to ensure uniform consistency of the mix. The final preparation will be a soft ball-like structure of 1 mm diameter. Resultant opaque paste has to be stored in airtight containers. If the mix turns translucent on storage, it has to be discarded. Group I (Experimental group I): LSTR with radicular instrumentation. Coronal and accessible radicular pulp tissue are extirpated using rotary files. After proper drying, the paste is placed in the cavity and canals. Group II (Experimental group II): LSTR with no radicular instrumentation. Only the coronal pulp is removed, the pulpal floor is covered with triple antibiotic paste with propylene glycol mix. Group III (Control group): Conventional pulpectomy. Pulp tissue extirpation is done. Biomechanical preparation is done using rotary files with frequent irrigation with Chlorhexidine. The canals are dried using sterile absorbent paper points followed by obturation by the paste of ZOE. For all groups: * The molar is then restored with glass ionomer and stainless steel crown. * Intraoral periapical radiographs are taken after completion of the procedure. * The children are recalled for clinical evaluation at the interval of 3,6,9,12 months; and radiographic evaluation at 6,12 months.

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