Chorioretinitis, Chorioretinopathy, Vitiligo
Conditions
Keywords
Vitiligo, Chorioretinitis
Brief summary
Vitiligo patients on systemic and local therapy may have some ocular adverse effects associated with the disease and its therapy.
Detailed description
Chorioretinal changes associated with vitiligo therapy could address patients visual acuity and life style. Early detection of these changes can help these patients to evade such adverse effects.
Interventions
DIAGNOSTIC_TESTOptical coherence tomography angiography (OCT-A)
Optical coherence tomography angiography scanning will be done for all subjects in the study.
Sponsors
Benha University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Inclusion criteria
* vitiligo patients on systemic and local therapy that regularly visit dermatology clinic at banha university. * normal subjects seeking regular ophthalmic examination at ophthalmology clinic at banha university.
Exclusion criteria
* patients with known chronic retinal diseases that may alter OCT-A parameters as age related macular degeneration and diabetic retinopathies. * patients that refuse to participate in this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of vessel density (VD) in superficial and deep retinal layer. | Immediately after OCT-A for each eye and at one month of follow-up. | Percentage (%) of superficial and deep vessel density changes in both groups measured by OCT-A software to asses retinal ischemia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Foveal avascular zone (FAZ) in millimeter (mm). | Immediately after OCT-A for each eye and at one month of follow-up. | Foveal avascular zone measurement in both groups in mm measured by OCT-A software. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Changes in visual acuity | Immediately after OCT-A for each eye and at one month of follow-up. | Visual acuity measurements in decimal form |
| Changes in choroidal thickness | Immediately after OCT-A for each eye and at one month of follow-up. | Choroidal thickness in mm. |
Countries
Egypt
Contacts
Primary ContactAhmed Abdelshafy, MD
Backup ContactAmal Yousif, MD
Outcome results
None listed